The nurse is instructing a patient with rheumatoid arthritis about a prescribed exercise program. Which information should the nurse include?
- A. Perform exercises every day, 3 to 10 times for every joint.
- B. Perform exercises even if inflammation is present.
- C. Perform exercises past the point of pain.
- D. Perform twice the number of exercises the next day if one day is missed.
Correct Answer: A
Rationale: The correct answer is A because a consistent exercise routine is important for managing rheumatoid arthritis. Performing exercises every day helps improve joint mobility and strength without causing excessive strain. Option B is incorrect as exercising during inflammation can worsen symptoms. Option C is incorrect as exercising past the point of pain can lead to injury. Option D is incorrect as overcompensating the following day can also lead to injury and disrupt the exercise program's consistency.
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What does the presence of carcinoembryonic antigens (CEAs) and α-fetoprotein (AFP) on cell membranes indicate has happened to the cells?
- A. They have shifted to more immature metabolic pathways and functions
- B. They have spread from areas of original development to different body tissues
- C. They produce abnormal toxins or chemicals that indicate abnormal cellular function
- D. They have become more differentiated as a result of repression of embryonic functions
Correct Answer: A
Rationale: The presence of CEAs and AFP indicates that cells have reverted to more immature metabolic pathways, characteristic of cancerous transformation.
Who introduced the concept of discrimination between self and non-self?
- A. Elie Metchnikoff
- B. Louis Pasteur
- C. Paul Ehrlich
- D. Charles Janeway
Correct Answer: C
Rationale: Paul Ehrlich introduced the concept of discrimination between self and non-self through his "horror autotoxicus" theory. He proposed that the immune system can differentiate between harmful non-self antigens and self-antigens. Ehrlich's theory laid the foundation for understanding immune responses and the development of immunology. Metchnikoff focused on phagocytosis, Pasteur on microbiology, and Janeway on innate immunity, not specifically on self vs. non-self discrimination.
What is the role of angiogenesis in cancer progression?
- A. Promotes tumor shrinkage
- B. Prevents metastasis
- C. Supports tumor growth by forming new blood vessels
- D. Reduces oxygen supply to the tumor
Correct Answer: C
Rationale: Angiogenesis supports tumor growth by forming new blood vessels to supply nutrients and oxygen.
The PAMP recognized by NOD1 is
- A. Flagellin
- B. CpG DNA
- C. Peptidoglycan
- D. K+ efflux
Correct Answer: C
Rationale: The correct answer is C: Peptidoglycan. NOD1 recognizes peptidoglycan, a component of bacterial cell walls. This recognition triggers an immune response. Flagellin (A) is recognized by TLR5, CpG DNA (B) is recognized by TLR9, and K+ efflux (D) is not a PAMP recognized by NOD1. Thus, only peptidoglycan is the correct choice for NOD1 recognition.
Innate behaviors are
- A. under strong genetic control
- B. performed in virtually the indifferent way by all individuals of a species
- C. Sociobiology
- D. the environment
Correct Answer: A
Rationale: The correct answer is A because innate behaviors are indeed under strong genetic control. These behaviors are instinctual and are genetically programmed in organisms. This genetic control ensures that all individuals of a species exhibit these behaviors consistently. Choice B is incorrect because while innate behaviors may be performed similarly by individuals of a species, there can still be variations. Choice C, Sociobiology, is incorrect as it is a branch of biology that studies social behavior in animals. Choice D, the environment, is incorrect as innate behaviors are not primarily influenced by the environment but rather by genetic factors.