The nurse is reviewing the immune system with a patient newly diagnosed with an autoimmune disorder. What should the nurse explain as the purpose of antibodies?
- A. They destroy foreign antigens.
- B. Work on many different antigens
- C. Are specific according to blood type
- D. Attach to antigens to label them for destruction
Correct Answer: D
Rationale: The correct answer is D. Antibodies attach to antigens to label them for destruction. This is crucial in the immune response to identify and mark harmful substances for elimination. Choice A is incorrect because antibodies do not destroy antigens directly. Choice B is incorrect as antibodies are specific to particular antigens. Choice C is incorrect as blood type specificity is determined by different antigens, not antibodies.
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A patient is scheduled to have a tunneled catheter placed for administration of chemotherapy for breast cancer. When preparing the patient for the catheter insertion, what does the nurse explain about this method of chemotherapy administration?
- A. Decreases the risk for extravasation at the infusion site
- B. Reduces the incidence of systemic side effects of the drug
- C. Does not become occluded as peripherally inserted catheters can
- D. Allows continuous infusion of the drug directly to the area of the tumor
Correct Answer: A
Rationale: Tunneled catheters reduce extravasation risks compared to peripheral lines by delivering medications centrally.
Which represents a correct grouping with respect to the target of an immune response, immune response strength, and resulting health status?
- A. Self-antigen, weak response, autoimmune disease
- B. Pathogen, strong response, recurrent infection
- C. Tumour antigen, weak response, cancer
- D. Transplanted organ, strong response, graft acceptance
Correct Answer: C
Rationale: Rationale:
1. Tumor antigens are non-self antigens that trigger a weak immune response due to immune tolerance.
2. Weak immune response against tumor antigens may lead to uncontrolled cell growth, resulting in cancer.
3. Strong immune responses are typically mounted against pathogens to clear infections.
4. Self-antigens should not trigger immune responses to prevent autoimmune diseases.
5. Transplanted organs can elicit strong immune responses leading to rejection, not acceptance.
Summary:
A - Incorrect: Self-antigens should not elicit immune responses to prevent autoimmune diseases.
B - Incorrect: Pathogens typically trigger strong immune responses to clear infections, not recurrent ones.
D - Incorrect: Transplanted organs often lead to strong immune responses and rejection, not acceptance.
The nurse is administering medications to a patient. Which medications should the nurse understand is being given to suppress C-reactive protein levels?
- A. Aspirin and steroids
- B. Antibiotics and diuretics
- C. Epinephrine and antihistamines
- D. Antihypertensives and antineoplastic agents
Correct Answer: A
Rationale: The correct answer is A: Aspirin and steroids. Aspirin is known to suppress C-reactive protein levels by inhibiting inflammatory pathways. Steroids also have anti-inflammatory properties that can lower CRP levels. Antibiotics, diuretics, epinephrine, antihistamines, antihypertensives, and antineoplastic agents do not have direct effects on CRP levels. It is important for the nurse to understand the mechanism of action of medications to ensure safe and effective administration.
All of the following are true about antibodies, EXCEPT which one?
- A. They fix complement.
- B. They occur on the surface of B-lymphocyte
- C. They predominate the primary immune response to antigen.
- D. have a single, defined amino acid sequence due to variability.
Correct Answer: D
Rationale: The correct answer is D because antibodies do not have a single, defined amino acid sequence due to variability in their structure. This variability is a result of somatic recombination and hypermutation.
A: Antibodies can fix complement, leading to the destruction of pathogens.
B: Antibodies are produced by B-lymphocytes and can occur on their surface as B-cell receptors.
C: Antibodies predominate the secondary immune response, not the primary response, as memory B-cells are generated during the primary response for a quicker and more robust secondary response.
Which condition is associated with increased susceptibility to bacterial infections due to complement deficiencies?
- A. Asthma
- B. Systemic lupus erythematosus (SLE)
- C. Streptococcus pneumoniae infections
- D. Chronic hepatitis
Correct Answer: C
Rationale: The correct answer is C: Streptococcus pneumoniae infections. Complement deficiencies impair the body's ability to fight bacterial infections, particularly encapsulated bacteria like Streptococcus pneumoniae. Asthma (A), SLE (B), and chronic hepatitis (D) are not directly associated with increased susceptibility to bacterial infections due to complement deficiencies. Asthma is a chronic respiratory condition, SLE is an autoimmune disease, and chronic hepatitis affects the liver. Therefore, only Streptococcus pneumoniae infections are directly linked to complement deficiencies.