Nokea
The endocrine gland(s) that makes insulin is the:
- A. pancreas
- B. adrenal glands
- C. thyroid gland
- D. pituitary gland
Correct Answer: A
Rationale: The correct answer is A: pancreas. The pancreas is responsible for producing insulin, a hormone that helps regulate blood sugar levels. It is located near the stomach and plays a crucial role in the endocrine system. The other choices (B: adrenal glands, C: thyroid gland, D: pituitary gland) do not produce insulin. Adrenal glands produce hormones like adrenaline and cortisol, thyroid gland produces hormones like thyroxine, and the pituitary gland produces various hormones that regulate other endocrine glands. Therefore, the pancreas is the only gland among the options that produces insulin, making it the correct answer.
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The person with _____ is most likely to receive insulin therapy.
- A. myxedema
- B. Graves’ disease
- C. diabetes insipidus
- D. hyperglycemia
Correct Answer: D
Rationale: The correct answer is D: hyperglycemia. Hyperglycemia refers to high blood sugar levels, a hallmark of diabetes mellitus. Insulin therapy is commonly prescribed to individuals with diabetes to help regulate their blood sugar levels. Myxedema (choice A) is associated with hypothyroidism, Graves' disease (choice B) is an autoimmune disorder affecting the thyroid, and diabetes insipidus (choice C) involves the kidneys and has no direct relation to insulin therapy for diabetes. Therefore, hyperglycemia is the most appropriate condition for receiving insulin therapy.
Estrogens and progesterone are produced by:
- A. the testes.
- B. the ovaries.
- C. the adrenal glands.
- D. the hypothalamus.
Correct Answer: B
Rationale: Estrogens and progesterone are primarily produced by the ovaries in females. The ovaries are the main reproductive organs responsible for the production of these hormones, essential for menstrual cycle regulation and pregnancy support. The correct answer is B because the ovaries are the key glands that synthesize and release estrogen and progesterone. Choices A, C, and D are incorrect because the testes primarily produce testosterone, the adrenal glands produce cortisol and adrenaline, and the hypothalamus is a brain region involved in hormone regulation, not hormone production.
Which is not Na+ dependent for absorption?
- A. thiamin
- B. riboflavin
- C. niacin
- D. folate
Correct Answer: D
Rationale: The correct answer is D. Folate absorption is not Na+ dependent because it is absorbed in the small intestine through a carrier-mediated process independent of sodium. Thiamin, riboflavin, and niacin require sodium-dependent transport mechanisms for absorption in the small intestine. Thiamin is absorbed through thiamin transporters that are Na+ dependent. Riboflavin is absorbed by sodium-dependent multivitamin transporters. Niacin absorption also involves sodium-dependent transporters. Therefore, folate is the only option that is not Na+ dependent for absorption.
Which of the following drugs has muscarinic and nicotinic actions and is resistant to hydrolysis by both true and pseudo cholinesterase:
- A. Acetylcholine
- B. Carbachol
- C. Bethanechol
- D. Succinylcholine
Correct Answer: B
Rationale: Step-by-step rationale for why B (Carbachol) is the correct answer:
1. Carbachol is a cholinergic drug that acts on both muscarinic and nicotinic receptors.
2. It is resistant to hydrolysis by both true and pseudo cholinesterase enzymes.
3. Acetylcholine (A) is rapidly hydrolyzed by both cholinesterases.
4. Bethanechol (C) is a muscarinic agonist but not a nicotinic agonist.
5. Succinylcholine (D) is a depolarizing neuromuscular blocking agent, not a cholinergic agonist.
Summary:
Carbachol is the only drug among the choices that has both muscarinic and nicotinic actions and is resistant to hydrolysis by cholinesterases. Acetylcholine is rapidly hydrolyzed, Bethanechol does not have nicotinic actions, and Succinyl
Hypersecretion of cortisol leads to:
- A. Addison’s disease
- B. Cushing’s syndrome
- C. Acromegaly
- D. Dwarfism
Correct Answer: B
Rationale: Step-by-step rationale for why choice B is correct:
1. Hypersecretion of cortisol is a hallmark of Cushing's syndrome.
2. Excessive cortisol levels can lead to symptoms like weight gain, high blood pressure, and muscle weakness.
3. Cushing's syndrome is characterized by an overactive adrenal gland producing too much cortisol.
4. Addison's disease (choice A) is caused by adrenal insufficiency, leading to low cortisol levels.
5. Acromegaly (choice C) is a growth hormone disorder, not related to cortisol.
6. Dwarfism (choice D) is typically due to growth hormone deficiency, not cortisol excess.
Summary:
Choice B is correct because hypersecretion of cortisol is specifically associated with Cushing's syndrome, causing a range of symptoms related to excess cortisol production. Choices A, C, and D are incorrect as they are not directly related to cortisol hypersecretion.