The patient is prescribed a medication that was just placed in Phase IV study. The patient tells the nurse, This medication is too expensive. Could the doctor order a generic form of this medication? What is the nurse's most accurate response?
- A. Medications are not produced in generic form until the patent expires, which normally takes several years.
- B. You can request the generic form but the binder used may make the drug less effective for this medication.
- C. The generic form of the medication would not be any less expensive because this is a relatively new medication.
- D. Generic medications are lower quality drugs and that would mean you would not be getting the best treatment available.
Correct Answer: A
Rationale: When a new drug enters the market, it is given a time-limited patent; generic forms of the medication cannot be produced until the patent expires. Because no generic version of this drug will exist because it is so new, it is impossible to predict what binder will be used or what the cost would be.
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Patrick is a 10-year-old patient who presents with uncomfortable constipation. Along with diet changes, a laxative is ordered to provide more rapid relief of constipation. An appropriate choice of medication for a 10-year-old child would be:
- A. PEG 3350 (Miralax)
- B. Bisacodyl (Dulcolax) suppository
- C. Docusate (Colace) suppository
- D. Polyethylene glycol electrolyte solution
Correct Answer: A
Rationale: PEG 3350 is safe and effective for kids; suppositories (B, C) are less preferred, and PEG solution is for bowel prep.
The typical response to intravenous injection of 5-HT in an anaesthetised animal is:
- A. Rise in BP
- B. Fall in BP
- C. Rise followed by brief fall in BP
- D. Sharp fall, followed by brief rise, followed by prolonged fall in BP
Correct Answer: D
Rationale: IV 5-HT (serotonin) typically causes a triphasic BP response in anesthetized animals: an initial sharp fall (vasodilation), a brief rise (vasoconstriction), and a prolonged fall (Bezold-Jarisch reflex).
A patient receiving gentamicin should be monitored for which potential adverse effect?
- A. Nephrotoxicity
- B. Hepatotoxicity
- C. Ototoxicity
- D. Both A and C
Correct Answer: D
Rationale: Gentamicin, an aminoglycoside, commonly causes nephrotoxicity and ototoxicity , requiring monitoring of renal function and hearing.
A nurse is providing discharge teaching to a client who has a new prescription for Clozapine. Which of the following statements should the nurse include in the teaching?
- A. You should have a high-carbohydrate snack between meals and at bedtime.
- B. You are likely to develop hand tremors if you take this medication for a long period of time.
- C. You may experience temporary to the first record of the first dose.
- D. You should have your white blood cell count monitored every week.
Correct Answer: D
Rationale: Clozapine requires weekly WBC monitoring due to risk of agranulocytosis.
The nurse administers amoxicillin 500 mg. The half-life of this drug is approximately 1 hour. At what point would the drug level in the body be 62.5 mg if the drug was not administered again?
- A. 1 hours after the original dose
- B. 2 hours after the original dose
- C. 3 hours after the original dose
- D. 4 hours after the original dose
Correct Answer: C
Rationale: The half-life of a drug is the time it takes for the amount of drug in the body to decrease to one-half of the peak level it previously achieved. At a dose of 500 mg the drug level would be 250 mg in 1 hour, 125 mg in 2 hours, 62.5 mg in 3 hours, and 31.25 mg in 4 hours so the correct answer is 3 hours.
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