Pediatric Nursing Practice Questions Related

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The physician orders tests to determine if a client has systemic lupus erythematosus (SLE). Which test result confirms SLE?

  • A. Increased total serum complement levels
  • B. An above-normal anti-deoxyribonucleic
  • C. Negative antinuclear antibody test acid
  • D. Negative lupus erythematosus cell test
Correct Answer: B

Rationale: An above-normal anti-deoxyribonucleic acid (anti-dsDNA) test result confirms systemic lupus erythematosus (SLE). Anti-dsDNA antibodies are highly specific for SLE and are found in about 70% of individuals with the condition. These antibodies target the genetic material within the cell nucleus and are strongly associated with lupus nephritis, a severe complication of SLE. Therefore, an elevated anti-dsDNA test result would be a key indicator of SLE diagnosis.