The term 'lymphocyte repertoire' refers to:
- A. The range of antigen receptor specificities found in a lymphocyte population
- B. The variety of effector functions that result from an adaptive immune response
- C. Antigen receptor specificities found on a given lymphocyte
- D. The collection of daughter cells produced when a lymphocyte divides after activation
Correct Answer: A
Rationale: The correct answer is A because the term 'lymphocyte repertoire' specifically refers to the range of antigen receptor specificities found in a lymphocyte population. Lymphocytes are immune cells that play a crucial role in recognizing and responding to antigens, and their diverse antigen receptor specificities allow them to recognize a wide range of pathogens. This term does not refer to effector functions (B) or a single lymphocyte's receptor specificities (C). Additionally, it does not describe the collection of daughter cells produced after division (D), as the repertoire refers to the initial diversity of antigen receptors within a lymphocyte population.
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Which of the following is NOT a function of the immune system?
- A. Promoting wound healing
- B. Fighting cancer
- C. Increasing pathogen reproduction
- D. Eliminating cell debris
Correct Answer: C
Rationale: The correct answer is C: Increasing pathogen reproduction. The immune system's main function is to protect the body from pathogens and foreign invaders, not to promote their reproduction. A: Promoting wound healing is correct as the immune system helps in tissue repair. B: Fighting cancer is correct as the immune system plays a role in recognizing and destroying cancerous cells. D: Eliminating cell debris is correct as the immune system helps in clearing out dead or damaged cells to maintain tissue health.
Match the immunoglobulins with their primary functions:
- A. 1-C, 2-A, 3-B, 4-D
- B. 1-B, 2-C, 3-D, 4-A
- C. 1-D, 2-B, 3-C, 4-A
- D. 1-A, 2-D, 3-B, 4-C
Correct Answer: A
Rationale: The correct answer is A: 1-C, 2-A, 3-B, 4-D. Immunoglobulins are antibodies with different functions:
1. IgG (C) - Main antibody in secondary immune response.
2. IgA (A) - Found in mucosal areas, neutralizes pathogens.
3. IgM (B) - First antibody produced in primary immune response.
4. IgE (D) - Involved in allergic reactions and defense against parasites. Other choices are incorrect as they mismatch the immunoglobulins with their functions.
During data collection, the nurse learns the patient is allergic to shellfish. Which precautions should be implemented during the patient's hospitalization?
- A. The patient should be placed in a private room.
- B. The kitchen should use dedicated equipment for all of the patient's food preparation.
- C. Iodine-based skin preparations should be replaced with different bactericidal cleansers.
- D. The patient's allergy should be noted on the medical record and communicated clearly to all caretakers.
Correct Answer: D
Rationale: Rationale:
1. The correct answer is D because it addresses the essential action of noting the patient's allergy on the medical record and communicating it to all caretakers to prevent inadvertent exposure.
2. Choice A is not necessary unless the patient's allergy poses an infection control risk that warrants isolation.
3. Choice B is excessive and not required as long as cross-contamination is prevented during food preparation.
4. Choice C is unrelated to the patient's shellfish allergy and not a standard precaution in this scenario.
What describes a primary use of biologic therapy in cancer treatment?
- A. Protect normal,rapidly reproducing cells of the gastrointestinal system from damage during chemotherapy
- B. Prevent the fatigue associated with chemotherapy and high-dose radiation as seen with bone marrow depression
- C. Enhance or supplement the effects of the host’s immune responses to tumor cells that produce flu-like symptoms
- D. Depress the immune system and circulating lymphocytes as well as increase a sense of well-being by replacing central nervous system deficits
Correct Answer: C
Rationale: Biologic therapy enhances the immune response against tumor cells, often causing flu-like symptoms.
Identify the incorrect statement in regard to immunoglobulins (Ig)
- A. Are made up of two identical light chains and two identical heavy chains
- B. Cannot recognize conformational antigens on viral particles
- C. Can recognize only exposed epitopes of pathogens
- D. Expressed early during B cell development on the membrane of B cell precursors (pre- B cells)
Correct Answer: B
Rationale: The correct answer is B because immunoglobulins can indeed recognize conformational antigens on viral particles. Immunoglobulins have variable regions that can bind to a wide range of antigen shapes. Choice A is correct as Ig structure consists of two light and two heavy chains. Choice C is incorrect as immunoglobulins can also bind to internal epitopes. Choice D is incorrect as Ig expression starts during the late B cell development stage.