Nokea
The U.S. Drug Enforcement Administration:
- A. Registers manufacturers and prescribers of controlled substances
- B. Regulates NP prescribing at the state level
- C. Sanctions providers who prescribe drugs off-label
- D. Provides prescribers with a number they can use for insurance billing
Correct Answer: A
Rationale: The DEA registers those handling controlled substances , not state NP rules , off-label sanctions , or insurance numbers .
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Glucocorticoids causes:
- A. Inhibition of lipolysis
- B. Disposition of fat in upper and lower extremities
- C. Atrophy of fatty tissue on face and paleness
- D. Catabolism of bone tissue
Correct Answer: D
Rationale: Glucocorticoids promote bone catabolism, leading to osteoporosis by inhibiting osteoblast activity and increasing osteoclast activity.
A nurse is caring for a client who takes Paroxetine to treat PTSD and reports that he grinds his teeth during the night. The nurse should identify which of the following interventions to manage Bruxism? (Select all that apply.)
- A. Concurrent administration of buspirone
- B. Administration of a different SSRI
- C. Use of a mouth guard
- D. Changing to a different class of antidepressant medication
Correct Answer: C
Rationale: A mouth guard is a practical intervention for bruxism; medication changes may not address it directly.
Jack, age 8, has attention deficit disorder (ADD) and is prescribed methylphenidate (Ritalin). He and his parents should be educated about the side effects of methylphenidate, which are:
- A. Slurred speech and insomnia
- B. Bradycardia and confusion
- C. Dizziness and orthostatic hypotension
- D. Insomnia and decreased appetite
Correct Answer: D
Rationale: Insomnia and appetite suppression are common methylphenidate side effects.
Protein binding of a drug helps in
- A. Distribution
- B. Prolonging half life
- C. Limiting metabolism
- D. All of the above
Correct Answer: D
Rationale: Protein binding affects distribution (bound drugs stay in plasma), prolongs half-life (less free drug available for clearance), and limits metabolism (bound drug is less accessible to enzymes).
Carbamazepine has a Black Box Warning recommending testing for the HLA-B*1502 allele in patients with Asian ancestry prior to starting therapy due to:
- A. Decreased effectiveness of carbamazepine in treating seizures in Asian patients with HLA-B*1502 allele
- B. Increased risk for drug interactions in Asian patients with the HLA-B*1502 allele
- C. Increased risk for Stevens-Johnson syndrome in Asian patients with HLA-B*1502 allele
- D. Patients who have the HLA-B*1502 allele being more likely to have a resistance to carbamazepine
Correct Answer: C
Rationale: HLA-B*1502 in Asians increases Stevens-Johnson syndrome risk with carbamazepine , per FDA warning, not efficacy or interactions .