Pediatric HESI Test Bank Related

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To whom is RhIG (RhoGAM) administered to prevent Rh isoimmunization?

  • A. Rh-negative women who deliver an Rh-positive newborn
  • B. Rh-positive women who deliver an Rh-negative newborn
  • C. Rh-negative newborns whose mothers are Rh positive
  • D. Rh-positive fathers before conception of second newborn when first newborn was Rh positive
Correct Answer: A

Rationale: RhIG (RhoGAM) is administered to Rh-negative women who deliver an Rh-positive newborn to prevent Rh isoimmunization. Rh isoimmunization can occur when an Rh-negative mother is exposed to Rh-positive fetal blood during childbirth, leading to the production of antibodies against Rh antigen. RhIG works by binding to and destroying any fetal Rh-positive red blood cells that have entered the mother's circulation, preventing her immune system from mounting an immune response and producing antibodies. This helps to protect subsequent pregnancies from complications related to Rh isoimmunization. Therefore, RhIG administration is crucial in preventing sensitization and ensuring the health of future pregnancies in Rh-negative women who deliver an Rh-positive newborn.