What aspect of pharmacology does a nurse study? (Select one that does not apply.)
- A. Adverse and anticipated drug effects
- B. Molecular pharmacology
- C. Impact of drugs on the body
- D. The bodys response to a drug
Correct Answer: B
Rationale: Nurses study pharmacology from a pharmacotherapeutic level, which includes the effect of drugs on the body, the bodys response to drugs, and both expected and unexpected drug effects. Chemical and molecular pharmacology (Options A and B) are not included in nursing pharmacology courses. Adverse and anticipated drug effects are part of pharmacotherapeutics, making C, D, and E correct.
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Pernicious anemia is treated with:
- A. Folic acid supplements
- B. Thiamine supplements
- C. Vitamin B12
- D. Iron
Correct Answer: C
Rationale: Pernicious anemia requires B12 due to absorption defect; folate masks it without fixing neuropathy.
A nurse is teaching a client who has a prescription for long-term use of oral prednisone for treatment of chronic asthma. The nurse should instruct the client to monitor for which of the following adverse effects of this medication?
- A. Weight gain
- B. Nervousness
- C. Bradycardia
- D. Constipation
Correct Answer: A
Rationale: Prednisone causes weight gain due to fluid retention and increased appetite.
The client has a PRN prescription for ondansetron (Zofran). For which condition should this medication be administered to the postoperative client?
- A. Paralytic ileus
- B. Incisional pain
- C. Urinary retention
- D. Nausea and vomiting
Correct Answer: D
Rationale: Ondansetron is an antiemetic used to treat postoperative nausea and vomiting, as well as nausea and vomiting associated with chemotherapy. The other options are incorrect.
A nurse is teaching a school-age child and his parents about a new prescription for Lisdexamfetamine. Which of the following information should the nurse include in the teaching? (Select one that does not apply.)
- A. An adverse effect of this medication is CNS stimulation.
- B. Administer the medication before bedtime.
- C. Monitor blood pressure while taking this medication.
- D. Increased dopamine leads to more activity
Correct Answer: B
Rationale: CNS stimulation , BP monitoring , and dopamine increase are key; it's taken in the morning, not bedtime.
A nurse is caring for a patient who has been receiving a drug by the intramuscular route but will receive the drug orally after discharge. How does the nurse explain the increased dosage prescribed for the oral dose?
- A. Passive diffusion
- B. Active transport
- C. Glomerular filtration
- D. First-pass effect
Correct Answer: D
Rationale: The first-pass effect involves drugs that are absorbed from the small intestine directly into the portal venous system, which delivers the drug molecules to the liver. After reaching the liver, enzymes break the drug into metabolites, which may become active or may be deactivated and readily excreted from the body. A large percentage of the oral dose is usually destroyed and never reaches tissues. Oral dosages account for the phenomenon to ensure an appropriate amount of the drug in the body to produce a therapeutic action. Passive diffusion is the major process through which drugs are absorbed into the body. Active transport is a process that uses energy to actively move a molecule across a cell membrane and is often involved in drug excretion in the kidney. Glomerular filtration is the passage of water and water-soluble components from the plasma into the renal tubule.