What does the nurse understand must occur in order to produce withdrawal syndrome?
- A. Addiction
- B. Craving
- C. Drug tolerance
- D. Physical dependence
Correct Answer: D
Rationale: Physical dependence causes withdrawal when a drug stops; addiction or tolerance don't suffice. Patients who develop a physical dependence on a drug will experience withdrawal syndrome when the drug is stopped.
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The nurse admits a patient to the unit and learns the patient has recently been diagnosed with chronic renal failure but has not informed the primary care provider of this diagnosis. What is the nurse's first priority?
- A. Administer medications ordered immediately.
- B. Maintain the patient's confidentiality.
- C. Call the admitting physician immediately.
- D. Provide teaching about chronic renal failure
Correct Answer: C
Rationale: Renal failure affects drug clearance; informing the physician ensures safe therapy adjustments.
The physician has asked a nurse to administer a drug intravenously to a patient who is unresponsive. How can the nurse ensure that the drug is administered to the right patient?
- A. By waking him up to ask him his name
- B. By identifying the patient's room number
- C. By checking the patient's wristband
- D. By asking the nursing assistant for the patient's location
Correct Answer: C
Rationale: The nurse should identify a patient by checking his wristband, which has the patient's name. The nurse should not ask the patient to confirm his name, because some patients, particularly those who are confused or have difficulty hearing, may respond by answering yes. Additionally, this patient is unresponsive. The nurse can obtain the patient's location by asking any other member of the health care staff, but should verify the patient's identity by checking the wristband. The nurse should not rely on the patient's room number alone.
Secobarbital and ethanol when given together show:
- A. Additive sedative action
- B. Reduced sedative action
- C. Competitive antagonism
- D. Chemical antagonism
Correct Answer: A
Rationale: Both secobarbital (barbiturate) and ethanol are CNS depressants, resulting in additive sedation.
Which of the following drugs interacts with nitroglycerine by inhibiting the metabolism of cGMP?
- A. Amyl nitrite
- B. Sildenafil
- C. Isosorbide mononitrate
- D. Nifedipine
Correct Answer: B
Rationale: Sildenafil, a PDE5 inhibitor, increases cGMP, enhancing nitroglycerin's hypotensive effect.
Drug which crosses the placental barrier is:
- A. Phenytoin
- B. Diazepam
- C. Corticosterioids
- D. All of the above
Correct Answer: D
Rationale: All listed drugs cross the placenta, affecting the fetus.