What is correct concerning TI:
- A. A safer drug has a higher theraputic index
- B. TI might be equal to 1
- C. The more the unwanted adverse effect, the ration decreases
- D. You are in danger if you take 1.8 ng/ml of Digoxin which has the margin of safety (0.8-2)
Correct Answer: A
Rationale: A higher therapeutic index indicates a greater margin of safety between therapeutic and toxic doses, making the drug safer.
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The nurse is explaining how medications work to a group of peers and explains that disruption of a single step in any enzyme system disrupts what?
- A. Cell life
- B. Cell membrane
- C. Cell receptor sites
- D. Cell function
Correct Answer: D
Rationale: If a single step in one of the many enzyme systems is blocked, normal cell function is disrupted. Cell life and cell membrane may be impacted by disruption of some enzymes but not all enzymes. Receptor sites would not be disrupted by disruption in a single step in the enzyme system.
A nurse in an emergency unit is reviewing the medical record of a client who is being evaluated for angle-closure Glaucoma. Which of the following findings are indicative of this condition?
- A. Insidious onset of painless loss of vision
- B. Gradual reduction in peripheral vision
- C. Severe pain around eyes
- D. Intraocular pressure 12 mm Hg
Correct Answer: C
Rationale: Angle-closure glaucoma presents with severe eye pain and elevated pressure, unlike the normal 12 mm Hg.
According to traditional Chinese medicine, if a person who has a fever is given a herb that is yang in nature, such as golden seal, the patient's illness will:
- A. Get worse
- B. Get better
- C. Not be adequately treated
- D. Need additional herbs to treat the yang
Correct Answer: A
Rationale: A yang (warming) herb like golden seal would worsen a fever, a yang condition.
A nurse's learning goals for the year include reviewing the most up-to-date information about emergency preparedness related to bioterrorism agents. What should the nurse do?
- A. Read textbooks devoted to the topic
- B. Review best practices around triage and emergency care
- C. Read journal articles about bioterrorism agents
- D. Visit the Centers for Disease Control and Prevention (CDC) Web site
Correct Answer: D
Rationale: The CDC website provides the most current, authoritative bioterrorism preparedness information.
Patients who are being treated with epoetin alfa need to be monitored for the development of:
- A. Thrombocytopenia
- B. Neutropenia
- C. Hypertension
- D. Gout
Correct Answer: C
Rationale: Epoetin alfa can cause hypertension by increasing red cell mass; blood count issues or gout are less common.