Nokea
What is the fraction of unchanged drug reaching the systemic circulation?
- A. Elimination
- B. Bioavailability
- C. Metabolism
- D. Drug displacement
Correct Answer: B
Rationale: Bioavailability is defined as the fraction of unchanged drug that reaches systemic circulation, a key pharmacokinetic parameter.
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Which statement(s) will be included when planning patient teaching regarding drug names?(Select one that does not apply.)
- A. Most drug companies place their products on the market under generic names
- B. The official name is the name under which the drug is listed by the US Food and Drug Administration (FDA)
- C. Brand names are easier to pronounce, spell, and remember
- D. The first letter of the generic name is not capitalized
Correct Answer: A
Rationale: The official name is listed by the FDA , brand names are easier for patients , and generic names are not capitalized . Most drugs are marketed under brand names, not generic.
The nurse, working on the maternity unit, receives a call from a pregnant woman asking how she can know whether a medication is safe to take while pregnant. What is the nurse's best response?
- A. You can take any drug indicated as a Category A.
- B. No medications should be taken during pregnancy.
- C. Never take medication until you receive approval from your health care provider.
- D. Most medications are safe but you need to weigh benefit against risk.
Correct Answer: C
Rationale: The best response to a pregnant woman asking about medication usage is to talk with her obstetric practitioner because the best advice will come from someone who knows their health and pregnancy history. While Category A drugs have no known risk, they may be contraindicated by the woman's health condition or pregnancy issues and many pregnant women would not know what it means to be a Category A drug. Medications can be helpful during pregnancy if taken safely and appropriately. Although risk benefit needs to be weighed, it should occur with advice from the obstetric practitioner.
Taking which drug with food maximizes it bioavailability?
- A. Donepezil
- B. Galantamine
- C. Rivastigmine
- D. Memantine
Correct Answer: C
Rationale: Rivastigmine's bioavailability is maximized with food, reducing GI side effects.
When a pharmacoeconomic analysis looks at two or more treatment alternatives that are considered equal in efficacy and compares the costs of each it is referred to as:
- A. Cost-minimization analysis
- B. Cost-of-illness analysis
- C. Cost-effectiveness analysis
- D. Cost-benefit analysis
Correct Answer: A
Rationale: Cost-minimization analysis compares costs of equally effective treatments.
A patient is ordered to receive a subcutaneous injection of heparin twice a day. When administering this drug to the patient, which of the following would be most important for the nurse to do to minimize tissue damage?
- A. Insert the needle at the appropriate angle.
- B. Select the needle length based on the patient's weight.
- C. Ensure that there is no hair on the injection site.
- D. Rotate the injection site regularly.
Correct Answer: D
Rationale: The nurse should rotate the injection sites to minimize the damage caused to the tissue. Inserting the needle at the proper angle and selecting the needle length based on the patient's weight will not significantly help in minimizing tissue damage if the same site is repeatedly injected. It is not necessary to avoid injection sites that have hair as long as the drug is administered in the upper arms, the upper abdomen, and the upper back.