What is the most likely congenital heart lesion in a newborn with Trisomy 21?
- A. AVSD
- B. Tetralogy of Fallot
- C. Ventricular septal defect
- D. Pulmonary stenosis
Correct Answer: A
Rationale: Atrioventricular septal defect (AVSD) is highly associated with Trisomy 21 and is the most likely congenital heart lesion in these infants.
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True statements about the use of the new Child Health Foundation growth charts include:
- A. Immediate referral is advised if the height of a child is on the second centile
- B. The midparental height of a child, whose parents are 176 and 160 cm tall, is 175 cm
- C. They can be used for all children including those with Down's syndrome
- D. The target centile range for a girl is midparental height ± 10 cm
Correct Answer: C
Rationale: The growth charts are designed to be inclusive and can be used for children with Down's syndrome, among others.
The predominant manifestations of primary pulmonary hypertension include the following EXCEPT
- A. exercise intolerance
- B. precordial chest pain
- C. syncope
- D. low arterial oxygen saturation
Correct Answer: B
Rationale: Precordial chest pain is not a typical manifestation of primary pulmonary hypertension.
The most common indication of heart transplantation in the neonate is
- A. Hypoplastic left heart syndrome
- B. Hypoplastic right heart syndrome
- C. Severe Ebstein's anomaly
- D. Dilated cardiomyopathy
Correct Answer: A
Rationale: Hypoplastic left heart syndrome is the most common indication for heart transplantation in neonates.
Regarding body iron stores:
- A. Serum ferritin is a poor guide to iron stores
- B. A healthy young man will have more iron stored as ferritin than in the circulating red cell mass
- C. Iron is the stimulant for ferritin production
- D. In iron deficiency, stores of haemosiderin are mobilised before ferritin
Correct Answer: C
Rationale: Iron is a key regulator for ferritin production, and as iron levels rise, ferritin synthesis is stimulated to store excess iron.
Patients at risk for bacterial endocarditis include those with all of the following EXCEPT
- A. repaired simple atrial septic defect
- B. aortic stenosis
- C. rheumatic fever heart disease
- D. palliative vascular shunts
Correct Answer: A
Rationale: Repaired simple atrial septal defects are not considered a risk for bacterial endocarditis unless there are residual defects.