Nokea
What role do cytokines play in innate immunity?
- A. They directly kill pathogens
- B. They act as signaling molecules to coordinate immune responses
- C. They only function in adaptive immunity
- D. They inhibit phagocytosis
Correct Answer: B
Rationale: The correct answer is B because cytokines act as signaling molecules to coordinate immune responses in innate immunity. They help regulate inflammation, activate immune cells, and promote clearance of pathogens. Option A is incorrect because cytokines do not directly kill pathogens. Option C is incorrect as cytokines play a crucial role in both innate and adaptive immunity. Option D is incorrect because cytokines do not inhibit phagocytosis; instead, they enhance this process to help eliminate pathogens.
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What determines a cell's response to a specific cytokine?
- A. The amount of antigen present
- B. The type of pathogen encountered
- C. The specific cytokine receptors expressed on the cell
- D. The tissue location of the immune cell
Correct Answer: C
Rationale: The correct answer is C because a cell's response to a specific cytokine is determined by the specific cytokine receptors expressed on the cell. Cytokine receptors are proteins on the cell surface that bind to specific cytokines, triggering intracellular signaling pathways that lead to various cellular responses. The amount of antigen present (A) is related to the initiation of the immune response but not the cell's response to cytokines. The type of pathogen encountered (B) may influence the overall immune response but not the specific response to cytokines. The tissue location of the immune cell (D) can affect the types of cytokines present in the microenvironment but does not directly determine the cell's response to a specific cytokine.
Identify the correct statement(s). In prokaryotes:
- A. Translation begins after transcription is finished.
- B. Messenger RNA is not co-linear with the DNA template.
- C. 5s, 16s, and 28s ribosomal RNA's are present.
- D. 50s and 30s ribosomal subunits are necessary for protein synthesis.
Correct Answer: d
Rationale: The correct answer is D because in prokaryotes, 50s and 30s ribosomal subunits combine to form the 70s ribosome, which is necessary for protein synthesis. Firstly, ribosomes are composed of two subunits, and in prokaryotes, these are the 50s and 30s subunits. Secondly, these subunits come together during translation to form the functional ribosome. Therefore, these ribosomal subunits are indeed necessary for protein synthesis in prokaryotes.
A: Incorrect. Translation can begin before transcription is finished in prokaryotes due to their lack of a nuclear membrane.
B: Incorrect. Messenger RNA in prokaryotes is co-linear with the DNA template as they do not undergo RNA splicing like eukaryotes.
C: Incorrect. In prokaryotes, the ribosomal RNA present is the 16s, 23s, and 5s, not 28s.
Which of the following is the most important factor in the nursing management of a client with CFS?
- A. Teaching the client how to avoid aggravating the disease
- B. Informing the client about the drug therapy that will provide significant improvement
- C. Advising the client to alter the diet and environment
- D. Educating the client about the disease process and its limitations
Correct Answer: D
Rationale: Educating the client about the disease process and its limitations helps them manage symptoms and improve quality of life.
Choose the correct sequence in an allergic reaction.
- A. Allergen → mast cells → histamine → B cells → IgE antibodies
- B. Allergen → IgE antibodies → B cells → histamine → mast cells
- C. Allergen → B cells → IgE antibodies → mast cells → histamine
- D. Allergen → histamine → mast cells → IgE antibodies → B cells
Correct Answer: C
Rationale: Rationale for Answer C:
1. Allergen exposure triggers B cells to produce IgE antibodies specific to the allergen.
2. IgE antibodies bind to mast cells sensitizing them.
3. Upon re-exposure to allergen, allergen binds to IgE on mast cells.
4. This triggers release of histamine and other chemicals causing allergic symptoms.
Summary:
- Choice A: Incorrect because B cells do not produce IgE antibodies before allergen exposure.
- Choice B: Incorrect because IgE antibodies are produced by B cells, not the other way around.
- Choice D: Incorrect because histamine is released after allergen binds to IgE on sensitized mast cells.
A 21-year-old patient says no one in his family has type 1 diabetes mellitus but he has had it since childhood. He asks how his diabetes was transmitted to him. The nurse should explain to him that this disease is
- A. a single gene disorder
- B. a chromosome disorder
- C. an acquired genetic disorder
- D. a multifactorial genetic disorder
Correct Answer: D
Rationale: Type 1 diabetes is considered a multifactorial genetic disorder influenced by multiple genes and environmental factors rather than being caused by a single gene or chromosome.