What type of antidepressant increases the availability of serotonin and norepinephrine by inhibiting enzymes that metabolize serotonin and norepinephrine?
Correct Answer: A
Rationale: The correct answer is A: Monoamine oxidase inhibitors (MAOIs). MAOIs work by inhibiting the enzyme monoamine oxidase, which is responsible for breaking down serotonin and norepinephrine. By inhibiting this enzyme, MAOIs increase the availability of serotonin and norepinephrine in the brain, leading to improved mood.
Incorrect choices:
B: Explosive occipital headache - This choice is irrelevant to the question and does not relate to antidepressants or neurotransmitter availability.
C: Polyuria - This choice is a symptom related to excessive urination and does not pertain to antidepressants or neurotransmitter metabolism.
D: Selective serotonin reuptake inhibitors (SSRIs) - While SSRIs also increase serotonin levels, they do so by blocking the reuptake of serotonin, not by inhibiting enzymes that metabolize serotonin and norepinephrine.