Nokea
When administering parenteral drugs, which of the following routes would the nurse use? (Select one that does not apply.)
- A. Subcutaneous
- B. Intramuscular
- C. Intradural
- D. Intravenous
Correct Answer: C
Rationale: A nurse can administer parenteral drugs via subcutaneous, intramuscular, intravenous, intradermal, and, in some instances, intra-arterial routes by means of a catheter placed by a physician in an artery. The primary health care provider can administer a drug via the intradural route.
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Patient education when prescribing clopidogrel includes:
- A. Do not take any herbal products without discussing it with the provider
- B. Monitor urine output closely and contact the provider if it decreases
- C. Clopidogrel can be constipating, use a stool softener if needed
- D. The patient will need regular anticoagulant studies while on clopidogrel
Correct Answer: A
Rationale: Herbal products can increase bleeding risk with clopidogrel; urine or constipation aren't typical issues, and INR isn't monitored.
A 43-year-old woman with Type-2 diabetes has been taking insulin with meals as well as metformin. Her blood glucose remains poorly controlled. Her doctor prescribes an additional drug, which is an analog of an endogenous peptide that enhances insulin secretion. What drug is this?
- A. Exenatide
- B. Glipizide
- C. Miglitol
- D. Pramlintide
Correct Answer: A
Rationale: Exenatide, a GLP-1 analog, enhances insulin secretion in a glucose-dependent manner, aiding type 2 diabetes control.
Which of the following shows high first pass metabolism:
- A. Propranolol
- B. Phenobarbitone
- C. Phenylbutazone
- D. Phenytoin
Correct Answer: A
Rationale: Propranolol undergoes extensive first-pass metabolism in the liver.
The nurse uses what term to describe the drug level required to have a therapeutic effect?
- A. Critical concentration
- B. Dynamic equilibrium
- C. Selective toxicity
- D. Active transport
Correct Answer: A
Rationale: A critical concentration of a drug must be present before a reaction occurs within the cells to bring about the desired therapeutic effect. A dynamic equilibrium is obtained from absorption of a drug from the site of drug entry, distribution to the active site, metabolism in the liver, and excretion from the body to have a critical concentration. Selective toxicity is the ability of a drug to attach only to those systems found in foreign cells. Active transport is the process that uses energy to actively move a molecule across a cell membrane and is often involved in drug excretion in the kidney.
B-Blockers are contra indicated in
- A. Hypertension
- B. Congestive cardiac failure
- C. Anxiety states
- D. Hyperthyroidis m
Correct Answer: B
Rationale: Beta-blockers worsen congestive heart failure.