When comparing angiotensin-converting enzyme (ACE) and angiotensin II receptor blocker (ARB) medications, which of the following holds true?
- A. Both have major issues with a dry, irritating cough
- B. Both contribute to some retention of potassium
- C. ARBs have a stronger impact on hypertension control than ACE medications
- D. ARBs have stronger diabetes mellitus renal protection properties than ACE medications
Correct Answer: B
Rationale: Both ACEIs and ARBs cause potassium retention due to reduced aldosterone.
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The nursing students are learning about the half-life of drugs. A student asks the instructor to explain half-life. What is the instructor's best response?
- A. Half-life of a drug is the time it takes for the amount of drug in the body to decrease to half of the peak level it previously achieved.
- B. Half-life is the amount of time it takes for the drug to be metabolized by the body.
- C. Half-life is the amount of time it takes for half of the drug to reach peak level in the body.
- D. Half-life of a drug is the time it takes for the drug to reach half its potential peak level in the body.
Correct Answer: A
Rationale: The half-life of a drug is the time it takes for the amount of drug in the body to decrease to half the peak level it previously achieved. Therefore Options B, C, and D are not correct.
Which of the following is natural mineralcorticoid:
- A. Methylprednisolone
- B. Betamethasone
- C. Triamcinolone
- D. Aldosterone
Correct Answer: D
Rationale: Aldosterone is the natural mineralocorticoid produced by the adrenal glands.
While caring for a patient scheduled for knee replacement surgery, the nurse provides cefazolin (Ancef) as ordered 30 minutes pre-operatively. The nurse knows that teaching has been effective by which of the following client statements?
- A. The antibiotic is given as a prophylactic to help reduce the risk of infection after surgery.'
- B. This is a palliative medication to help ease the pain from surgery.'
- C. This medication will replace vitamins and minerals that may be lost due to bleeding during surgery.'
- D. This medication will help the surgeon identify areas of bone destruction due to arthritis.'
Correct Answer: A
Rationale: Cefazolin is administered pre-operatively as prophylaxis to prevent surgical site infections, aligning with standard practice and effective patient understanding.
The nurse knows that which medication requires monitoring of thyroid function?
- A. Dofetilide
- B. Amiodarone
- C. Sotalol
- D. Flecainide
Correct Answer: B
Rationale: Amiodarone can cause hypo- or hyperthyroidism due to its iodine content, necessitating thyroid function monitoring.
Which of the following drugs should be used only when clearly needed in pregnant and breastfeeding women?
- A. Memantine
- B. Pyridostigmine
- C. Galantamine
- D. Rivastigmine
Correct Answer: B
Rationale: Pyridostigmine's safety in pregnancy/breastfeeding is less established, requiring caution.