When describing the different classes of diuretics, the nursing instructor would include which of the following as sulfonamides, with nonbacteriostatic action, that inhibit the enzyme carbonic anhydrase? Select all that apply.
- A. Furosemide
- B. Acetazolamide
- C. Hydrochlorothiazide
- D. Methazolamide
- E. Torsemide
Correct Answer: B,D
Rationale: Acetazolamide and methazolamide are carbonic anhydrase inhibitors. Furosemide and torsemide are loop diuretics. Hydrochlorothiazide is a thiazide diuretic.
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A nurse is providing care to a client who has an allergy to sulfamethoxazole/trimethoprim. The nurse understands that the client may have cross-sensitivity reactions with which of the following diuretics? Select all that apply.
- A. Chlorothiazide
- B. Furosemide
- C. Chlorthalidone
- D. Metolazone
- E. Spironolactone
Correct Answer: A,C,D
Rationale: A cross-sensitivity reaction may occur with the thiazides (chlorothiazide, chlorthalidone, and metolazone) and sulfonamides (sulfamethoxazole).
A primary health care provider has prescribed a loop diuretic for a client with hypertension. The client also has diabetes mellitus. The nurse would assess the client for which of the following after administering the drug?
- A. Sudden pain in the joints
- B. Increased blood glucose levels
- C. Occurrence of gout attacks
- D. Sudden increase in weight
Correct Answer: B
Rationale: The nurse should monitor for increased blood glucose levels in the diabetic client receiving a loop diuretic.
A nurse is administering a diuretic that inhibits reabsorption of sodium and chloride ions in the distal and proximal tubules and in the loop of Henle. Which of the following might the nurse be administering? Select all that apply.
- A. Chlorothiazide
- B. Furosemide
- C. Bumetanide
- D. Mannitol
- E. Spironolactone
Correct Answer: B,C
Rationale: Loop diuretics, like furosemide (Lasix) and bumetanide (Bumex), cause diuresis by inhibiting reabsorption of sodium and chloride ions in the distal and proximal tubules and in the loop of Henle.
A nurse is administering acetazolamide to a client. The nurse understands that this drug leads to excretion of which of the following? Select all that apply.
- A. Sodium
- B. Magnesium
- C. Potassium
- D. Bicarbonate
- E. Chloride
Correct Answer: A,C,D
Rationale: Carbonic anhydrase inhibitors, like acetazolamide, result in the excretion of sodium, potassium, bicarbonate, and water.
A nurse suspects that a client who is receiving acetazolamide is developing hyponatremia based on assessment of which of the following? Select all that apply.
- A. Bradycardia
- B. Anorexia
- C. Hypotension
- D. Hypoglycemia
- E. Decreased skin turgor
Correct Answer: C,E
Rationale: The following are signs of hyponatremia: cold, clammy skin; decreased skin turgor; confusion; hypotension; irritability; and tachycardia.
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