Disorders of the Genitourinary System Related

Review Disorders of the Genitourinary System related questions and content

Which antibiotic course is inappropriate for clinical scenario?

  • A. Acute simple cystitis - trimethoprim for 3 days in otherwise well young women.
  • B. Acute uncomplicated pyelonephritis - gentamycin + amoxicillin IV initially followed by 7 days of Augmentin orally.
  • C. Pregnancy associated cystitis - nitrofurantoin 5 mg QID for 14 days.
  • D. Acute simple cystitis in male patients - Augmentin or trimethoprim for 14 days.
Correct Answer: B

Rationale: The correct answer is B because the antibiotic regimen for acute uncomplicated pyelonephritis should not include gentamycin due to its potential toxicity and nephrotoxicity. The initial use of IV gentamycin is not recommended for uncomplicated pyelonephritis. The combination of gentamycin and amoxicillin is not the standard treatment for this condition. Gentamycin should be reserved for more serious infections. The choice of Augmentin for 7 days orally is also not the standard of care for pyelonephritis. The other choices (A, C, D) are appropriate antibiotic regimens for the corresponding clinical scenarios.