Which bacteria is known for causing a disease characterized by a pseudomembrane in the throat?
- A. Clostridium tetani
- B. Bordetella pertussis
- C. Corynebacterium diphtheriae
- D. Streptococcus pyogenes
Correct Answer: C
Rationale: The correct answer is C: Corynebacterium diphtheriae. This bacterium causes diphtheria, a disease characterized by a pseudomembrane in the throat. This pseudomembrane is a result of the bacterial exotoxins causing inflammation and necrosis of the throat tissues. Clostridium tetani (A) causes tetanus, characterized by muscle stiffness, not a pseudomembrane in the throat. Bordetella pertussis (B) causes whooping cough, with symptoms of severe coughing fits but no pseudomembrane. Streptococcus pyogenes (D) causes strep throat, but does not produce a pseudomembrane.
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Which bacteria produce exotoxins that affect the nervous system?
- A. Clostridium botulinum and Clostridium tetani
- B. Escherichia coli and Salmonella
- C. Bacillus anthracis and Listeria monocytogenes
- D. Pseudomonas aeruginosa and Staphylococcus aureus
Correct Answer: A
Rationale: The correct answer is A: Clostridium botulinum and Clostridium tetani. Both bacteria produce exotoxins that affect the nervous system. Clostridium botulinum produces botulinum toxin, causing botulism, leading to muscle paralysis. Clostridium tetani produces tetanospasmin, causing tetanus, leading to muscle stiffness and spasms.
Choice B (Escherichia coli and Salmonella) are known for causing gastrointestinal infections, not specifically affecting the nervous system. Choice C (Bacillus anthracis and Listeria monocytogenes) produce toxins that primarily affect other body systems, not the nervous system. Choice D (Pseudomonas aeruginosa and Staphylococcus aureus) are associated with skin and respiratory infections, not neurological effects.
A lot of pyoinflammatory processes in oral cavity are caused by anaerobes. What nutrient medium can be used for control of wound textile contamination by anaerobes?
- A. Kitt-Tarozzi
- B. Endo
- C. Roux
- D. Sabouraud's
Correct Answer: A
Rationale: The correct answer is A: Kitt-Tarozzi. This medium contains blood and hemin, which are essential nutrients for the growth of anaerobes. Blood provides a source of iron, while hemin stimulates the growth of anaerobes. This combination creates an environment conducive for the isolation and identification of anaerobic organisms.
B: Endo and C: Roux are selective media primarily used for the isolation of gram-negative bacteria and not specifically designed for anaerobes.
D: Sabouraud's is a medium used for the cultivation of fungi, not anaerobes.
In summary, Kitt-Tarozzi is the correct choice due to its specific nutrient composition that supports the growth of anaerobes, unlike the other options which are not suitable for this purpose.
Which of the antibiotics listed below are not suitable for treatment of listeriosis?
- A. Penicillin and ampicillin
- B. Macrolids
- C. Cephalosporins
- D. None of them
Correct Answer: B
Rationale: The correct answer is B: Macrolides. Listeriosis is typically treated with antibiotics such as Penicillin and ampicillin due to their effectiveness against Listeria monocytogenes. Macrolides, on the other hand, are not first-line agents for listeriosis treatment. They are less effective in treating this bacterial infection compared to Penicillin and ampicillin. Cephalosporins may also be less effective against Listeria monocytogenes compared to Penicillin and ampicillin. Choice D is incorrect as Macrolides are not suitable for listeriosis treatment.
Which of the following proteins are encoded by herpesviruses and required for viral DNA replication?
- A. viral DNA polymerase
- B. ribonucleotide reductase
- C. neuraminidase
- D. thymidine kinase
Correct Answer: A
Rationale: The correct answer is A: viral DNA polymerase. This enzyme is essential for replicating the viral DNA during the herpesvirus life cycle. It catalyzes the synthesis of new DNA strands using the viral genomic template. Ribonucleotide reductase (B) is involved in nucleotide synthesis, but not directly in DNA replication. Neuraminidase (C) is an enzyme found in influenza viruses, not herpesviruses. Thymidine kinase (D) is an enzyme that phosphorylates thymidine, but its role is more related to nucleotide metabolism rather than viral DNA replication.
Acne is caused by:
- A. Staphylococcus aureus
- B. Staphylococcus epidermidis
- C. Streptococcus pyogenes
- D. Propionibacterium acnes
Correct Answer: D
Rationale: The correct answer is D: Propionibacterium acnes. This bacterium plays a key role in acne formation by colonizing hair follicles, leading to inflammation and acne lesions. It produces fatty acids that contribute to the development of acne. Staphylococcus aureus (A) and Staphylococcus epidermidis (B) are not directly linked to acne. Streptococcus pyogenes (C) is associated with skin infections but not acne. In summary, Propionibacterium acnes is the primary bacterium responsible for acne due to its ability to induce inflammation and follicular blockages.
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