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Which bacteria produce exotoxins that affect the nervous system?

  • A. Clostridium botulinum and Clostridium tetani
  • B. Escherichia coli and Salmonella
  • C. Bacillus anthracis and Listeria monocytogenes
  • D. Pseudomonas aeruginosa and Staphylococcus aureus
Correct Answer: A

Rationale: The correct answer is A: Clostridium botulinum and Clostridium tetani. Both bacteria produce exotoxins that affect the nervous system. Clostridium botulinum produces botulinum toxin, causing botulism, leading to muscle paralysis. Clostridium tetani produces tetanospasmin, causing tetanus, leading to muscle stiffness and spasms.

Choice B (Escherichia coli and Salmonella) are known for causing gastrointestinal infections, not specifically affecting the nervous system. Choice C (Bacillus anthracis and Listeria monocytogenes) produce toxins that primarily affect other body systems, not the nervous system. Choice D (Pseudomonas aeruginosa and Staphylococcus aureus) are associated with skin and respiratory infections, not neurological effects.