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Which clinical manifestations are consistently observed in infants who have been diagnosed with congenital hypothyroidism? Select all that apply.

  • A. Irritability
  • B. Hoarse cry
  • C. Bradycardia
  • D. Constipation
  • E. Fused fontanels
  • F. Excessive sleeping
Correct Answer: B,C,D,F

Rationale: The infant with congenital hypothyroidism may display the following signs: skin mottling, a large fontanel, a large tongue, hypotonia, slow reflexes, bradycardia, and a distended abdomen. Other signs and symptoms include prolonged jaundice, lethargy, constipation, feeding problems, coldness to touch, umbilical hernia, hoarse cry, and excessive sleeping.