Basic Immune System Quizlet Related

Review Basic Immune System Quizlet related questions and content

Which enzyme catalyzes the addition of deoxynucleotides to the 3'OH ends of DNA molecules?

  • A. Phosphohydrolase
  • B. T4 DNA ligase
  • C. Terminal deoxynucleotidyl transferase
  • D. DNA endonuclease
Correct Answer: C

Rationale: The correct answer is C: Terminal deoxynucleotidyl transferase (TdT). TdT catalyzes the addition of deoxynucleotides to the 3'OH ends of DNA molecules. It does so by adding nucleotides in a template-independent manner, making it crucial for generating diversity in immune cell receptor genes.

A: Phosphohydrolase - This enzyme is not involved in adding deoxynucleotides to DNA ends.
B: T4 DNA ligase - This enzyme catalyzes the joining of DNA fragments, not the addition of deoxynucleotides.
D: DNA endonuclease - This enzyme cleaves DNA internally, not involved in adding deoxynucleotides to DNA ends.