Nokea
Which of the following bacteria produces an endotoxin responsible for septic shock?
- A. Staphylococcus aureus
- B. Escherichia coli
- C. Neisseria meningitidis
- D. All of the above
Correct Answer: D
Rationale: The correct answer is D, "All of the above." Staphylococcus aureus, Escherichia coli, and Neisseria meningitidis all produce endotoxins that can lead to septic shock. Endotoxins are part of the outer membrane of Gram-negative bacteria, such as E. coli and N. meningitidis, which can trigger a severe immune response leading to septic shock. S. aureus, a Gram-positive bacterium, produces toxins that can also contribute to septic shock. Therefore, all of these bacteria can produce endotoxins responsible for septic shock. Choices A, B, and C are incorrect because they only identify individual bacteria that produce endotoxins, whereas the correct answer encompasses all bacteria listed.
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All are correct except:
- A. Spotted fevers can be caused by Rickettsia mooseri and Rickettsia provazekii
- B. The Q-fever is transmitted only after ticks bite
- C. The Mediterranean fever is present with maculopapular rash
- D. None of the above
Correct Answer: B
Rationale: The correct answer is B because Q-fever is not transmitted only after ticks bite; it can also be transmitted through inhalation of contaminated aerosols. Rickettsia mooseri and Rickettsia provazekii can cause spotted fevers, making choice A correct. Mediterranean fever is associated with a recurrent pattern of fever, not maculopapular rash, making choice C incorrect. "None of the above" is not correct in this case as choice B is incorrect.
All statements about plasmids are correct except:
- A. Many plasmids contain genes that confer resistance to one or more antibiotics
- B. Are smaller, circular, extrachromosomal DNAs
- C. Plasmids encode essential bacteria properties
- D. Plasmids are responsible for the bacterial conjugation
Correct Answer: C
Rationale: The correct answer is C because plasmids do not encode essential bacterial properties. They are non-essential, extra-chromosomal DNA molecules that can replicate independently within bacterial cells. Plasmids mainly contain genes for antibiotic resistance, genetic transfer, and other specific functions. Choice A is correct as many plasmids do carry antibiotic resistance genes. Choice B is also accurate as plasmids are indeed smaller, circular, and exist outside the bacterial chromosome. Choice D is true as plasmids can facilitate bacterial conjugation, allowing the transfer of genetic material between bacteria.
Erysipelas is a bacterial infection characterised by well-defined areas of bright-red, inflamed and rough or leathery skin. Which one is the causative agent:
- A. Pseudomonas aeruginosa
- B. Staphylococcus aureus
- C. Streptococcus pyogenes
- D. Candida albicans
Correct Answer: C
Rationale: Step-by-step rationale for Choice C (Streptococcus pyogenes) being the correct answer:
1. Erysipelas is a skin infection characterized by well-defined red, inflamed skin areas.
2. Streptococcus pyogenes is a common causative agent of erysipelas.
3. This bacterium produces enzymes that break down skin proteins, leading to the characteristic symptoms of erysipelas.
4. Streptococcus pyogenes is known for causing skin infections, including erysipelas.
Summary of why the other choices are incorrect:
A. Pseudomonas aeruginosa: Typically causes opportunistic infections, but not commonly associated with erysipelas.
B. Staphylococcus aureus: Can cause skin infections, but not typically associated with erysipelas.
D. Candida albicans: Fungal infection, not a bacterium, and not known to cause erysipelas.
A patient with a long history of chronic gastritis undergoes a gastroscopy, which detects an ulcer in the duodenum area. Microscopic examination of the tissue biopsy developed Gram-negative curved bacteria and the rapid urease activity test of the biopsy material was highly positive. The most likely cause of the disease is:
- A. Vibrio cholerae
- B. Campylobacter fetus
- C. Acinetobacter baumannii
- D. Helicobacter pylori
Correct Answer: D
Rationale: The correct answer is D: Helicobacter pylori. Helicobacter pylori is a known bacterium associated with causing duodenal ulcers. The presence of Gram-negative curved bacteria in the biopsy along with a highly positive rapid urease test is characteristic of H. pylori infection. Vibrio cholerae causes cholera, not duodenal ulcers. Campylobacter fetus is associated with gastroenteritis, not duodenal ulcers. Acinetobacter baumannii is a nosocomial pathogen, not typically associated with duodenal ulcers. In summary, the unique combination of findings in this case points towards H. pylori as the most likely cause of the disease.
Disinfection with chemicals acting on cell surface:
- A. Soaps
- B. Phenols
- C. Amines
- D. Polymyxin
Correct Answer: B
Rationale: The correct answer is B: Phenols. Phenols act on the cell surface by disrupting cell membranes and denaturing proteins, leading to cell death. Soaps (A) work by lifting dirt and microbes off surfaces, not directly acting on cell surfaces. Amines (C) are typically used as disinfectants targeting specific enzymes in microbes, not cell surfaces. Polymyxin (D) is an antibiotic that works by disrupting cell membranes internally, not on the cell surface.