Nokea
Which of the following does albumin have the strongest affinity for?
- A. Anionic drugs
- B. Hydrophilic drugs
- C. Hydrophobic drugs
- D. A and C
Correct Answer: C
Rationale: Albumin has the strongest affinity for hydrophobic drugs , which bind to its hydrophobic pockets, unlike hydrophilic drugs; anionic drugs may bind but less preferentially.
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Ototoxicity is more likely if aminoglycosides are administered with which of the following drug classes?
- A. Loop diuretics
- B. Metformin
- C. Vancomycin
- D. Cephalosporins
Correct Answer: A
Rationale: Loop diuretics (e.g., furosemide) enhance aminoglycoside ototoxicity by increasing inner ear damage risk.
If the measles, mumps, rubella, and varicella (MMRV) combined vaccine is ordered to be given as the first MMR and varicella dose to a child the CDC recommends:
- A. Parents be informed of the increased risk of fever and febrile seizures over the MMR plus varicella two-shot regimen
- B. Patients must also receive MMRV as the second dose of MMR and varicella in order to build adequate immunity
- C. Patients be premedicated with acetaminophen 15 minutes before the vaccine is given
- D. Patients should not be around pregnant women for the first 48 hours after the vaccine is given
Correct Answer: A
Rationale: MMRV has higher fever/seizure risk vs. separate shots, per CDC; second dose isn't mandated as MMRV.
Before administering a prescription medication, what information does the nurse find on the drug label? (Select all that apply.)
- A. Brand name
- B. Generic name
- C. Drug concentration
- D. Adverse effects
Correct Answer: D
Rationale: Prescription drug labels will contain the brand name, generic name, drug concentration, and expiration date. Adverse effects will not be listed on drug labels.
Which phenothiazine has the least extra pyramidal effect
- A. Thioridazine
- B. Chlorpromazine
- C. Triflupromazine
- D. Fluphenazine
Correct Answer: A
Rationale: Thioridazine has fewer extrapyramidal effects.
The nurse transcribes an order to administer Valium 10 mg IV stat. This order is correctly interpreted by the nurse to mean it should be provided how? (Select all that apply.)
- A. As needed
- B. Immediately
- C. One time only
- D. Intravenously
Correct Answer: D
Rationale: The stat order is generally used on an emergency basis. It means that the drug is to be administered as soon as possible, but only once. IV indicates the route is intravenous. A PRN order means administer if needed. The order would specify divided doses and amount per dose if indicated.