Which of the following does NOT describe Cephalosporins
- A. relatively broad spectrum
- B. bactericidal
- C. beta-lactam
- D. interferes with protein synthesis
Correct Answer: D
Rationale: The correct answer is D: interferes with protein synthesis. Cephalosporins are beta-lactam antibiotics that work by inhibiting bacterial cell wall synthesis, not protein synthesis. They are bactericidal and have a relatively broad spectrum of activity against various bacteria. Choice A, B, and C all describe characteristics of cephalosporins, making them incorrect options.
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Microscopy of a sputum smear revealed acid-fast bacilli stained red using the Ziehl-Neelsen method. What is the most likely diagnosis?
- A. Tuberculosis
- B. Leprosy
- C. Diphtheria
- D. Pneumonia
Correct Answer: A
Rationale: The presence of acid-fast bacilli stained red using the Ziehl-Neelsen method indicates a mycobacterial infection. Among the choices, tuberculosis is the most common mycobacterial infection affecting the lungs, presenting with acid-fast bacilli in sputum. Leprosy is caused by Mycobacterium leprae, but it typically does not show up in sputum smears. Diphtheria is caused by Corynebacterium diphtheriae, which is not acid-fast. Pneumonia is a general term for lung inflammation caused by various pathogens, not specifically mycobacteria. Therefore, the correct diagnosis is tuberculosis based on the microscopy findings.
Which of the following bacteria is associated with foodborne illnesses?
- A. Clostridium botulinum
- B. Salmonella enterica
- C. Escherichia coli
- D. All of the above
Correct Answer: D
Rationale: The correct answer is D (All of the above) because all three bacteria mentioned (Clostridium botulinum, Salmonella enterica, Escherichia coli) are associated with foodborne illnesses. Clostridium botulinum causes botulism, Salmonella enterica causes salmonellosis, and Escherichia coli can cause food poisoning. Each of these bacteria can contaminate food and lead to illnesses when consumed. Therefore, selecting all of the above is the correct choice. The other choices (A, B, C) are incorrect because each of those bacteria individually is associated with foodborne illnesses.
What preparations are used for prevention of fungal infection?
- A. Fluconozol, Orungal, Nisoral
- B. Rubomycin, Bleomycin, Mytomycin C
- C. Cytosar, Cormyctin, Lomycitin
- D. Captopril, Enalapril
Correct Answer: A
Rationale: The correct answer is A because Fluconazole, Orungal, and Nizoral are antifungal medications commonly used for prevention of fungal infections. Fluconazole is a systemic antifungal agent, Orungal (Itraconazole) is used for various fungal infections, and Nizoral (Ketoconazole) is effective against a wide range of fungal infections. Choices B, C, and D do not contain antifungal medications and are unrelated to preventing fungal infections.
Which of the following viruses belong to the family Herpesviridae?
- A. Epstein-Barr virus
- B. Poxvirus
- C. SARS
- D. HIV
Correct Answer: A
Rationale: Step-by-step rationale for the correct answer (A: Epstein-Barr virus):
1. Epstein-Barr virus is a member of the Herpesviridae family, known for causing infectious mononucleosis.
2. Members of Herpesviridae have double-stranded DNA genomes and enveloped virions.
3. They establish latent infections in host cells and can reactivate periodically.
4. Poxvirus (B) belongs to the Poxviridae family, not Herpesviridae.
5. SARS (C) is caused by a coronavirus, not a herpesvirus.
6. HIV (D) belongs to the Retroviridae family, not Herpesviridae.
Summary: The correct answer is A because Epstein-Barr virus is a member of the Herpesviridae family, exhibiting specific characteristics distinct from the other choices.
In preparation for business trip abroad the doctor was prescribed a histoschizontocidal antimalarial drug as a personal means of disease prevention. What drug was given to the doctor?
- A. Chingamin
- B. Mefloquine
- C. Biseptol (Co-Trimoxazole)
- D. Quinine
Correct Answer: B
Rationale: The correct answer is B: Mefloquine. Mefloquine is a histoschizontocidal antimalarial drug commonly prescribed for prevention of malaria in travelers. It is effective against the liver stage of the malaria parasite, which is crucial for preventing the development of the disease. Chingamin (A) is not a commonly used antimalarial drug. Biseptol (C) is a combination antibiotic and is not effective against malaria parasites. Quinine (D) is primarily used for treating malaria, not preventing it, and it is not specifically histoschizontocidal.