Nokea
Which of the following drug is a radical curative in plasmodium vivax malaria and is used as prophylaxis for malaria at Chloroquine sensitive regions
- A. Quinine
- B. Primaquine
- C. Mefloquine
- D. Chloroquine
Correct Answer: B
Rationale: The correct answer is B: Primaquine. Primaquine is a radical curative drug for Plasmodium vivax malaria, targeting the liver stage of the parasite to prevent relapse. It is also used as prophylaxis in Chloroquine sensitive regions due to its effectiveness against both the liver and blood stages of the parasite. Quinine (A) is mainly used for treating severe malaria. Mefloquine (C) is used for prophylaxis but not as a radical curative for Plasmodium vivax. Chloroquine (D) is effective against Plasmodium vivax but not as a radical curative.
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Which disease causes connective tissue changes that cause glomerulonephritis?
- A. Gout
- B. Amyloidosis
- C. Diabetes mellitus
- D. Systemic lupus erythematosus
Correct Answer: D
Rationale: The correct answer is D: Systemic lupus erythematosus (SLE). SLE is an autoimmune disease that can affect multiple organs, including the kidneys. In SLE, the immune system attacks healthy tissues, leading to inflammation and damage to the connective tissues in the kidneys, resulting in glomerulonephritis. Gout (A) is a form of arthritis caused by the buildup of uric acid crystals, not directly related to glomerulonephritis. Amyloidosis (B) is a condition where abnormal protein deposits can accumulate in organs, but it does not primarily cause glomerulonephritis. Diabetes mellitus (C) can lead to diabetic nephropathy, a common cause of kidney damage, but it does not directly cause glomerulonephritis associated with connective tissue changes.
A patient is being treated with furosemide and Digoxin because of CHF. She * developed UTI. Which of the following antibiotics should NOT be prescribed?
- A. Cotrimoxazole
- B. Ciprooxacin
- C. Gentamycin
- D. Ampicillin
Correct Answer: C
Rationale: The correct answer is C: Gentamycin. Gentamycin is not recommended in this case due to its potential for nephrotoxicity, especially in patients already receiving furosemide. Furosemide is a loop diuretic that can also cause kidney damage, so combining it with Gentamycin increases the risk of further renal impairment. Cotrimoxazole (A) and Ampicillin (D) are commonly used antibiotics that do not have significant interactions with furosemide and Digoxin. Ciprofloxacin (B) is a fluoroquinolone antibiotic that is generally safe to use in patients with CHF and UTI.
When performing a genitourinary assessment on a 16-year-old male adolescent, the nurse notices a
- A. abdominal pressure and decreases when he is lying down. The patient complains of pain when straining. The nurse knows that this description is most consistent
- C. Femoral
- D. Incisional Test Bank - Physical Examination and Health Assessment 8e (by Jarvis) 394
Correct Answer: A
Rationale: The correct answer is A because the description provided suggests inguinal hernia. Abdominal pressure causing pain, worsening when standing or straining, and relief when lying down are classic symptoms of inguinal hernia. This is common in males, especially adolescents, due to the descent of the testes through the inguinal canal. Choices B, C, and D do not align with the symptoms of an inguinal hernia and are therefore incorrect. Option A stands out as the best choice based on the specific symptoms presented in the question.
Which antibiotics should be avoided in patients of liver disease?:
- A. Tetracycline
- B. Cotrimoxazole
- C. Cephalexin
- D. Ethanbutol
Correct Answer: A
Rationale: The correct answer is A: Tetracycline. Tetracycline should be avoided in patients with liver disease due to its potential hepatotoxicity. Tetracycline is primarily metabolized in the liver and can exacerbate liver damage in patients with pre-existing liver conditions. Cotrimoxazole, Cephalexin, and Ethambutol are generally considered safe for use in patients with liver disease as they are not known to cause significant liver toxicity.
In a patient with AKI, which laboratory urinalysis result indicates tubular damage?
- A. Hematuria
- B. Specific gravity fixed at 1.010
- C. Urine sodium of 12 mEq/L (12 mmol/L)
- D. Osmolality of 1000 mOsm/kg (1000 mmol/kg)
Correct Answer: C
Rationale: The correct answer is C: Urine sodium of 12 mEq/L (12 mmol/L). In a patient with AKI, tubular damage results in the inability of the kidneys to reabsorb sodium effectively, leading to a low urine sodium concentration. This is because damaged tubules cannot properly regulate sodium reabsorption. Choices A, B, and D do not directly indicate tubular damage. Hematuria (choice A) can be seen in various renal conditions, fixed specific gravity at 1.010 (choice B) may indicate dilute urine, and osmolality of 1000 mOsm/kg (choice D) could be within normal range depending on the clinical context.