Nokea
Which of the following drugs can be used in cases of beta blocker overdose?
- A. Glucagon
- B. Flumazenil
- C. Deferoxamine
- D. Naloxone
Correct Answer: A
Rationale: Glucagon increases cardiac contractility via a non-beta receptor pathway, making it effective in beta-blocker overdose.
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Which of the following statements about leukotriene pathway inhibitors in
- A. They are more potent anti-inflammatory agents than corticosteroids
- B. Have less side effects than corticosteroids
- C. Are contraindicated in children below 10 years of age
- D. Have no role in aspirin induced asthma
Correct Answer: B
Rationale: Leukotriene inhibitors have fewer side effects than corticosteroids.
Patients should be instructed regarding the rapid onset of zolpidem (Ambien) because:
- A. Zolpidem should be taken just before going to bed.
- B. Zolpidem may cause dry mouth and constipation.
- C. Patients may need to double the dose for effectiveness.
- D. They should stop drinking alcohol at least 30 minutes before taking zolpidem.
Correct Answer: A
Rationale: Zolpidem's rapid onset requires bedtime administration to prevent falls or amnesia.
Hepatitis B vaccine is contraindicated in patients who:
- A. Were born after less than 32 weeks gestation (give first dose at age 6 months)
- B. Are pregnant
- C. Are on hemodialysis
- D. Are allergic to yeast
Correct Answer: D
Rationale: Hepatitis B vaccine is contraindicated in yeast allergy (it's yeast-derived); prematurity , pregnancy , or dialysis are not.
A characteristic that distinguishes true receptors from other drug binding sites present in blood and other biological tissues is the characteristic of:
- A. binding affinity
- B. reversible binding
- C. signal transduction
- D. stereoselective interaction
Correct Answer: B
Rationale: Reversible binding is a key feature of true receptors, distinguishing them from non-specific binding sites like plasma proteins.
Reduce the likelihood of therapeutic failure with tamoxifen treatment
- A. Not provided in document
- B. Not provided in document
- C. Not provided in document
- D. Not provided in document
Correct Answer: B
Rationale: This question lacks options, but the answer key (ANS: 2) suggests the second choice. Strategies to reduce therapeutic failure include avoiding CYP2D6 inhibitors to ensure proper metabolism of tamoxifen to its active form.