Nokea
Which of the following drugs is considered a first-generation cephalosporin?
- A. Cefepime
- B. Cefazolin
- C. Ceftriaxone
- D. Cephalexin
Correct Answer: B
Rationale: Cefazolin is a first-generation cephalosporin, effective against Gram-positive bacteria, unlike cefepime (fourth) or ceftriaxone (third).
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In the presence of naloxone, a higher concentration of morphine is required to elicit full pain relief. Naloxone by it self has no effect. Which of the following is correct regarding these medications?
- A. Naloxone is a competitive antagonist
- B. Morphine is a full agonist, and naloxone is a partial agonist
- C. Morphine is less efficacious than is naloxone
- D. Morphine is less potent than is naloxone
Correct Answer: A
Rationale: Naloxone shifts morphine's dose-response curve rightward (increased EC50), typical of competitive antagonism, with no intrinsic effect.
A nurse assessing a client's IV catheter insertion site notes a hematoma. Which of the following actions should the nurse take? (Select all that apply.)
- A. Stop the infusion.
- B. Apply alcohol to the insertion site.
- C. Apply warm compresses to the insertion site
- D. Lower the client's arm.
Correct Answer: C
Rationale: Warm compresses and elevation reduce swelling and promote absorption of a hematoma.
A nurse is teaching the parents of a child who has a new prescription for Desipramine. The nurse should instruct the parents that which of the following adverse effects is the priority to report to the provider?
- A. Constipation
- B. Suicidal thoughts
- C. Photophobia
- D. Dry mouth
Correct Answer: B
Rationale: Suicidal thoughts are a critical adverse effect of tricyclics like desipramine, requiring immediate reporting.
Alcohol should not be given with
- A. Sulphonamides
- B. Clonidine
- C. Reserpine
- D. Metronidazole
Correct Answer: D
Rationale: Metronidazole with alcohol causes a disulfiram-like reaction (flushing, nausea).
To reduce potential adverse effects, patients taking a peripherally acting alpha1 antagonist should do all of the following EXCEPT:
- A. Take the dose at bedtime
- B. Sit up slowly and dangle their feet before standing
- C. Monitor their blood pressure and skip a dose if the pressure is less than 120/80
- D. Weigh daily and report weight gain of greater than 2 pounds in one day
Correct Answer: C
Rationale: Skipping doses based on blood pressure is not recommended; it risks uncontrolled hypertension.