Nokea
Which of the following drugs is CORRECTLY paired with its ECG effects?
- A. Lidocaine; decreased QRS and PR intervals
- B. Metoprolol: increased QRS duration
- C. Flecainide: increased PR, QRS, and QT intervals
- D. Verapamil: increased PR interval
Correct Answer: D
Rationale: Verapamil slows AV conduction, increasing PR interval.
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The nursing students are learning about the half-life of drugs. A student asks the instructor to explain half-life. What is the instructor's best response?
- A. Half-life of a drug is the time it takes for the amount of drug in the body to decrease to half of the peak level it previously achieved.
- B. Half-life is the amount of time it takes for the drug to be metabolized by the body.
- C. Half-life is the amount of time it takes for half of the drug to reach peak level in the body.
- D. Half-life of a drug is the time it takes for the drug to reach half its potential peak level in the body.
Correct Answer: A
Rationale: The half-life of a drug is the time it takes for the amount of drug in the body to decrease to half the peak level it previously achieved. Therefore Options B, C, and D are not correct.
Monitoring for a patient being prescribed iron for iron deficiency anemia includes:
- A. Reticulocyte count 1 week after therapy is started
- B. Complete blood count every 2 weeks throughout therapy
- C. Hemoglobin level at 1 week of therapy
- D. INR weekly throughout therapy
Correct Answer: A
Rationale: Reticulocyte count at 1 week assesses iron therapy response; CBC or hemoglobin checks are later, and INR is irrelevant.
Beta 2 adrenergic receptor agonists:
- A. Relieve bronchospasms
- B. Potentiates hypertensive
- C. Catecholamine inhibits the reception
- D. Have porasympathominetic action on bronchi
Correct Answer: A
Rationale: Beta-2 adrenergic agonists, like salbutamol, relieve bronchospasms by relaxing bronchial smooth muscle, making them key in asthma and COPD management.
While taking an angiotensin II receptor blocker (ARB), patients need to avoid certain over-the-counter drugs without first consulting the provider because:
- A. Cimetidine is metabolized by the CYP 3A4 isoenzymes
- B. Nonsteroidal anti-inflammatory drugs reduce prostaglandin levels
- C. Both 1 and 2
- D. Neither 1 nor 2
Correct Answer: B
Rationale: NSAIDs reduce prostaglandins, counteracting ARB's renal protective effects.
When comparing angiotensin-converting enzyme (ACE) and angiotensin II receptor blocker (ARB) medications, which of the following holds true?
- A. Both have major issues with a dry, irritating cough
- B. Both contribute to some retention of potassium
- C. ARBs have a stronger impact on hypertension control than ACE medications
- D. ARBs have stronger diabetes mellitus renal protection properties than ACE medications
Correct Answer: B
Rationale: Both ACEIs and ARBs cause potassium retention due to reduced aldosterone.