Nokea
Which of the following drugs used to treat Alzheimer's disease is not an anticholinergic?
- A. Donepezil
- B. Memantine
- C. Rivastigmine
- D. Galantamine
Correct Answer: B
Rationale: Memantine is an NMDA receptor antagonist, not an anticholinesterase like the others.
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What factor influences drug absorption?
- A. Kidney function
- B. Route of administration
- C. Liver function
- D. Cardiovascular function
Correct Answer: B
Rationale: Drug absorption is influenced by the route of administration. IV administration is the fastest method; drug absorption is slower when given orally. Kidney function impacts excretion, liver function impacts metabolism, and cardiovascular function impacts distribution.
A nurse is preparing to administer clindamycin 200 mg by intermittent IV bolus. The amount available is clindamycin injection 200 mg in 100 mL 0.9% sodium chloride (0.9% NaCl) to infuse over 30 min. The nurse should set the IV pump to deliver how many mL/hr? (Round the answer to the nearest whole number. Do not use a trailing zero.)
- A. 200
- B. 180
- C. 250
- D. 500
Correct Answer: A
Rationale: Calculation: (100 mL / 30 min) 60 min/hr = 200 mL/hr, matching the provided answer.
A patient is prescribed lidocaine for ventricular arrhythmias. Which side effect should the nurse monitor for?
- A. Hypotension
- B. Nausea
- C. Seizures
- D. Bradycardia
Correct Answer: C
Rationale: Lidocaine, a Class IB antiarrhythmic, can cause CNS side effects like seizures at high doses, a key monitoring point.
A prescription needs to be written for:
- A. Legend drugs
- B. Most controlled drugs
- C. Medical devices
- D. All of the above
Correct Answer: D
Rationale: Prescriptions are required for legend drugs (prescription-only), most controlled drugs, and certain medical devices , per regulatory standards.
The following is the antithyroid mechanism of action of mercazolil:
- A. Inbits thyrotropic hormone production in pituitary
- B. Inhibits thyroid hormone synthesis in thyroid gland
- C. Interfere follicule cells in thyroid gland
- D. Interfere iod reaptake in thyroid gland
Correct Answer: B
Rationale: Mercazolil (methimazole) inhibits thyroid hormone synthesis by blocking thyroperoxidase activity in the thyroid.