Nokea
Which of the following is a representative of sulfonylurea?
- A. Merformin
- B. Glibenclamide
- C. Acarbose
- D. Liraglutide
Correct Answer: B
Rationale: Glibenclamide is a sulfonylurea that stimulates insulin release from beta cells.
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The average starting dose of warfarin is 5 mg daily. Higher doses of 7.5 mg daily should be considered in which patients?
- A. Pregnant women
- B. Elderly men
- C. Overweight or obese patients
- D. Patients with multiple comorbidities
Correct Answer: C
Rationale: Overweight/obese patients may need higher warfarin doses due to larger volume of distribution; pregnancy contraindicates warfarin.
Under new U.S. Food and Drug Administration labeling, Pregnancy Categories will be:
- A. Strengthened with a new coding such as C+ or C- to discern when a drug is more or less toxic to the fetus
- B. Changed to incorporate a pregnancy risk summary and clinical considerations on the drug label
- C. Eliminated, and replaced with a link to the National Library of Medicine TOXNET Web site for in-depth information regarding pregnancy concerns
- D. Clarified to include information such as safe dosages in each trimester of pregnancy
Correct Answer: B
Rationale: FDA replaced categories with risk summaries and clinical considerations for clearer, narrative-based guidance, effective 2015.
A nurse in a provider's office is reviewing the medical record of a client who is pregnant and is at her first prenatal visit. Which of the following immunizations may the nurse administer safely to this client?
- A. Varicella vaccine
- B. Rubella vaccine
- C. Inactivated influenza vaccine
- D. Measles vaccine
Correct Answer: C
Rationale: Inactivated influenza vaccine is safe in pregnancy; live vaccines (A, B, D) are contraindicated.
Which statement is not correct regarding acarbose:
- A. Is for internal use
- B. Inhibiting alfa glucosidase
- C. Inhibits carbohydrates absorbtion in the gut
- D. Is effective for diabetes mellitus type I
Correct Answer: D
Rationale: Acarbose is primarily effective for type 2 diabetes by delaying carbohydrate absorption, not type 1, which relies on insulin deficiency.
A nurse is preparing to administer a prescribed medication to a client. The nurse integrates knowledge of which of the following as a possible factor that could influence the drug response?
- A. Age
- B. Polypharmacy
- C. Weight
- D. All the above
Correct Answer: D
Rationale: Drug response can be influenced by the following factors: age, polypharmacy, weight, sex, disease, and genetics.