Nokea
Which of the following is not related to drug toxicity of Atenolol?
- A. CHF
- B. Tachycardia
- C. AV block
- D. Sedative appearance
Correct Answer: B
Rationale: The correct answer is B: Tachycardia. Atenolol is a beta-blocker that works by slowing down the heart rate, so tachycardia is not related to its toxicity. A: CHF can be exacerbated by Atenolol due to its negative inotropic effects. C: AV block can occur as Atenolol can further slow down the heart's conduction system. D: Sedative appearance can be a side effect of Atenolol due to its action on the central nervous system. In summary, tachycardia is not related to Atenolol toxicity because it decreases heart rate.
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Which of the following is not a side effect of the ACE Inhibitor (Captopril)?
- A. Rash
- B. Angioedema
- C. Cough
- D. Congestion
Correct Answer: D
Rationale: The correct answer is D: Congestion. ACE Inhibitors like Captopril do not typically cause congestion as a side effect. The main reason is that ACE inhibitors work by dilating blood vessels, which helps reduce blood pressure and improve blood flow. Congestion is more commonly associated with conditions like allergies or upper respiratory infections.
A: Rash - Possible side effect of ACE inhibitors, but not specific to Captopril.
B: Angioedema - Rare but serious side effect of ACE inhibitors, including Captopril.
C: Cough - Common side effect of ACE inhibitors due to increased bradykinin levels.
Which of the following is the primary site of activity for the drug Warfarin?
- A. Kidney
- B. Liver
- C. Blood
- D. Heart
Correct Answer: B
Rationale: The correct answer is B: Liver. Warfarin is primarily metabolized in the liver by the cytochrome P450 enzyme system. The liver is responsible for breaking down and activating many drugs, including Warfarin. It is where the drug's metabolism and effects are most significant. The other choices are incorrect because Warfarin's main site of activity is in the liver, not the kidney, blood, or heart. The kidney mainly excretes the drug, while the blood carries it throughout the body, and the heart is not directly involved in Warfarin's metabolism.
Which of the following is not an effect of the drug isoflurane?
- A. Elevated lipid levels
- B. Nausea
- C. Increased blood flow to the brain
- D. Decreased respiratory function
Correct Answer: A
Rationale: The correct answer is A: Elevated lipid levels. Isoflurane does not cause elevated lipid levels. Isoflurane is a general anesthetic that primarily affects the central nervous system, leading to effects like decreased respiratory function and increased blood flow to the brain. Nausea can also be a side effect of isoflurane due to its impact on the gastrointestinal system. However, there is no direct link between isoflurane and elevated lipid levels. Thus, choice A is the correct answer.
Which of the following conditions is not treated with epinephrine?
- A. Renal disease
- B. Asthma
- C. Hypotension
- D. Glaucoma
Correct Answer: A
Rationale: The correct answer is A: Renal disease. Epinephrine is not used to treat renal disease because it can potentially worsen kidney function. Epinephrine is used in asthma to dilate the airways, in hypotension to increase blood pressure, and in glaucoma to reduce intraocular pressure. Treating renal disease with epinephrine can lead to further complications due to its effect on blood flow and kidney function. Therefore, renal disease is not treated with epinephrine to avoid exacerbating kidney issues.
A drug ending in the suffix (tidine) is considered a ______.
- A. Antidepressant
- B. Protease inhibitor
- C. Beta antagonist
- D. H antagonist
Correct Answer: D
Rationale: The correct answer is D: H antagonist. Drugs ending in the suffix (tidine) typically belong to the class of histamine H2-receptor antagonists. These drugs work by blocking the action of histamine on H2 receptors in the stomach, reducing the production of stomach acid. This is commonly used to treat conditions such as peptic ulcers and gastroesophageal reflux disease.
Explanation of other choices:
A: Antidepressant - Drugs ending in (pramine) or (ine) are more commonly associated with antidepressants.
B: Protease inhibitor - Drugs ending in (navir) are typically protease inhibitors used in antiviral therapy.
C: Beta antagonist - Drugs ending in (olol) are beta-blockers, which are used to treat conditions such as hypertension and heart disease, not related to (tidine) suffix.