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Which of the following patients is at the greatest risk of developing acute kidney injury? A patient who

  • A. has been on aminoglycosides for the past 6 days
  • B. has a history of controlled hypertension with a blood pressure of 138/88 mm Hg
  • C. was discharged 2 weeks earlier after aminoglycoside therapy of 2 weeks
  • D. has a history of fluid overload as a result of heart failure
Correct Answer: C

Rationale: The correct answer is C because the patient was recently discharged after a prolonged course of aminoglycoside therapy, which is a known risk factor for acute kidney injury due to its nephrotoxic effects. Choice A is incorrect because although aminoglycosides can cause kidney injury, the duration of therapy is shorter in this case. Choice B is incorrect because controlled hypertension is not a significant risk factor for acute kidney injury. Choice D is incorrect because fluid overload from heart failure may lead to other complications but is not directly associated with acute kidney injury.