Which of the following scientists performed the first vaccination against smallpox?
- A. Pasteur
- B. Jenner
- C. Semmelweis
- D. Koch
Correct Answer: B
Rationale: The correct answer is B: Jenner. Edward Jenner performed the first vaccination against smallpox in 1796 by using cowpox virus to immunize individuals. He observed that milkmaids who had contracted cowpox did not get smallpox, leading to the development of the smallpox vaccine. Pasteur is known for germ theory, Semmelweis for handwashing in healthcare, and Koch for identifying the causative agents of diseases. However, none of them performed the first smallpox vaccination like Jenner.
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Infectious disease' is:
- A. Clinical term
- B. A term expressing the possibility of developing certain symptoms in an infection
- C. A+B
- D. No correct answer
Correct Answer: C
Rationale: The correct answer is C because "Infectious disease" is a combination of both a clinical term (A) and a term expressing the possibility of developing certain symptoms in an infection (B). Infectious diseases are illnesses caused by pathogenic microorganisms, such as bacteria, viruses, parasites, or fungi, that can spread directly or indirectly from person to person. Therefore, the term encompasses both the clinical aspect of the disease and the potential symptoms that may manifest in an infected individual. Choices A and B alone do not fully capture the comprehensive definition of infectious disease, making C the correct answer. Choice D is incorrect as there is a correct answer in this case.
A child is presumably ill with diphtheria. A specimen of affected mucous membrane of his pharynx was taken for analysis. The smear was stained and microscopic examination revealed yellow rods with dark blue thickenings on their ends. What structural element of a germ cell was revealed in the detected microorganisms?
- A. Volutin granules
- B. Plasmids
- C. Capsule
- D. Spores
Correct Answer: A
Rationale: The correct answer is A: Volutin granules. Volutin granules are metachromatic granules that stain dark blue with methylene blue or Leishman stain. In diphtheria-causing bacteria, Corynebacterium diphtheriae, these granules are typically seen as yellow rods with dark blue thickenings on their ends when stained. Volutin granules are storage inclusions composed of polymetaphosphate that serve as an energy reserve for the bacteria. The presence of these granules in the detected microorganisms indicates the characteristic feature of Corynebacterium diphtheriae.
Summary of other choices:
B: Plasmids are extrachromosomal DNA molecules that are not typically visible on stained smears.
C: Capsules are outer protective layers that are not visible on stained smears.
D: Spores are reproductive structures formed by certain bacteria, not typically seen in Corynebacterium diphtheriae.
Which of the following eyewash/safety showers should be used for immediate flushing only, until the victim reaches another safety unit?
- A. Emergency shower
- B. Personal eyewash
- C. Handheld drench hose
- D. Combination unit
Correct Answer: B
Rationale: The correct answer is B: Personal eyewash. Personal eyewash is designed for immediate flushing until the victim reaches a more suitable safety unit. It provides a controlled flow of water to safely flush eyes while transporting the victim. The emergency shower (A) is meant for full-body coverage, not just for the eyes. Handheld drench hose (C) may not provide adequate flushing pressure. Combination unit (D) may not be easily portable for immediate use.
Babesiosis is a vector-borne, malaria-like illness caused by a:
- A. bacterium
- B. virus
- C. helminth
- D. protozoan
Correct Answer: D
Rationale: The correct answer is D: protozoan. Babesiosis is caused by a protozoan parasite called Babesia. Protozoans are single-celled organisms that can cause various diseases in humans. Babesiosis is transmitted to humans through the bite of infected ticks. Bacteria (choice A), viruses (choice B), and helminths (choice C) are not responsible for causing babesiosis. Bacteria are typically responsible for diseases like Lyme disease, viruses for illnesses like Zika, and helminths for infections such as parasitic worms. Thus, the correct choice for the causative agent of babesiosis is a protozoan.
Which of the following diseases can be transmitted by a tick?
- A. Botulism
- B. Anthrax
- C. Tularemia
- D. MRSA
Correct Answer: C
Rationale: The correct answer is C: Tularemia. Ticks can transmit tularemia, a bacterial infection caused by Francisella tularensis. Ticks pick up the bacteria when feeding on infected animals and can then transmit it to humans through their bites. Botulism (A) is caused by toxins produced by Clostridium botulinum bacteria, not transmitted by ticks. Anthrax (B) is a bacterial infection caused by Bacillus anthracis, typically transmitted through contact with contaminated animal products. MRSA (D) is a bacterial infection caused by Staphylococcus aureus, commonly transmitted through direct contact with infected individuals or contaminated surfaces, not by ticks.