Nokea
Which of the following statements about NSAIDs is true?
- A. Most NSAIDs are weak acids
- B. Most NSAIDs are metabolised by the liver into inactive metabolites
- C. Oxicams tend to have the longest half-lives of all NSAIDs
- D. All of the above
Correct Answer: D
Rationale: All are true: NSAIDs are weak acids, metabolized by the liver, and oxicams (e.g., piroxicam) have long half-lives.
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Tick the substance which changes the activity of an effector element but doesn't belong to second messengers:
- A. cAMP
- B. cGMP
- C. G-protein
- D. Calcium ions
Correct Answer: C
Rationale: G-protein is a transducer, not a second messenger, unlike cAMP, cGMP, and calcium.
The American Dietetic Association recommends pregnant women take a supplement including:
- A. 1,000 IU daily of vitamin D
- B. 2.4 mcg/day of vitamin B12
- C. 600 mcg/day of folic acid
- D. 8 mg/day of iron
Correct Answer: C
Rationale: 600 mcg/day of folic acid is recommended during pregnancy to prevent neural tube defects.
While caring for a patient scheduled for knee replacement surgery, the nurse provides cefazolin (Ancef) as ordered 30 minutes pre-operatively. The nurse knows that teaching has been effective by which of the following client statements?
- A. The antibiotic is given as a prophylactic to help reduce the risk of infection after surgery.'
- B. This is a palliative medication to help ease the pain from surgery.'
- C. This medication will replace vitamins and minerals that may be lost due to bleeding during surgery.'
- D. This medication will help the surgeon identify areas of bone destruction due to arthritis.'
Correct Answer: A
Rationale: Cefazolin is administered pre-operatively as prophylaxis to prevent surgical site infections, aligning with standard practice and effective patient understanding.
Which of the following are well-perfused tissues?
- A. Brain
- B. Skeletal
- C. Bone
- D. Adipose
Correct Answer: A
Rationale: The brain is a well-perfused tissue due to its high blood flow, unlike skeletal muscle (moderate), bone (low), and adipose (poorly perfused).
Cost-effectiveness analysis compares two or more treatments or programs that are:
- A. Not necessarily therapeutically equivalent
- B. Considered equal in efficacy
- C. Compared with the dollar value of the benefit received
- D. Expressed in terms of patient preference or quality-adjusted life years
Correct Answer: A
Rationale: Cost-effectiveness analysis evaluates treatments that may differ in efficacy.