Which of the following statements about NSAIDs is true?
- A. Most NSAIDs are weak acids
- B. Most NSAIDs are metabolised by the liver into inactive metabolites
- C. Oxicams tend to have the longest half-lives of all NSAIDs
- D. All of the above
Correct Answer: D
Rationale: All are true: NSAIDs are weak acids, metabolized by the liver, and oxicams (e.g., piroxicam) have long half-lives.
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Infants and young children are at higher risk of ADRs due to:
- A. Immature renal function in school-age children
- B. Lack of safety and efficacy studies in the pediatric population
- C. Children's skin being thicker than adults, it is less likely to absorb dosages of topical medication
- D. Infant boys having a higher proportion of muscle mass, leading to a higher volume of distribution
Correct Answer: B
Rationale: Lack of pediatric studies increases ADR risk due to unestablished safety/efficacy, unlike renal maturity , skin thickness (C, false), or muscle mass (D, false).
Which of the following drugs is CORRECTLY paired with its ECG effects?
- A. Lidocaine; decreased QRS and PR intervals
- B. Metoprolol: increased QRS duration
- C. Flecainide: increased PR, QRS, and QT intervals
- D. Verapamil: increased PR interval
Correct Answer: D
Rationale: Verapamil slows AV conduction, increasing PR interval.
The nurse is checking the medical record of an assigned patient for medication orders. The nurse is unable to read the primary health care provider's handwriting. Which action would be most appropriate?
- A. The nurse should question the order with the primary health care provider.
- B. The nurse should try to interpret the handwriting.
- C. The nurse should confirm the order with a nearby health care provider.
- D. The nurse should obtain a verbal order.
Correct Answer: A
Rationale: Any order that is unclear, particularly due to illegible handwriting, should be questioned. The nurse should not try to interpret the handwriting as it may lead to a misinterpretation. The nurse should also not confirm the order with any other physician who is nearby. Administering drugs based on verbal orders is permissible only during emergencies.
A nurse is caring for an older adult client who has a new prescription for Digoxin and takes multiple other medications. The nurse should recognize that concurrent use of which of the following medications places the client at risk for Digoxin toxicity?
- A. Phenytoin
- B. Verapamil
- C. Warfarin
- D. Aluminum hydroxide
Correct Answer: B
Rationale: Verapamil increases digoxin levels by reducing clearance, risking toxicity.
A nurse in the post-anesthesia care unit is caring for a client who is experiencing malignant hyperthermia. Which of the following actions should the nurse take?(Select one that does not apply.)
- A. Place a cooling blanket on the client.
- B. Administer oxygen at 100%.
- C. Administer iced 0.9% sodium chloride.
- D. Administer blood, 0.1% sodium chloride.
Correct Answer: D
Rationale: Cooling , oxygen , iced saline , and temperature monitoring manage malignant hyperthermia.