Nokea
Which of the following statements about Thalidomide is INCORRECT?
- A. It is anti angiogenic
- B. It is anti inflammatory
- C. It is immunomodulatory
- D. It is mitogenic
Correct Answer: D
Rationale: Thalidomide is not mitogenic; it inhibits cell proliferation.
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Which of the following is NOT true regarding ligand-gated ion channels?
- A. React quickly to a stimulus or ligand
- B. Can have intracellular binding sites
- C. Can exhibit allosteric binding
- D. Open or close in response to deformations in the cell membrane
Correct Answer: D
Rationale: Ligand-gated channels respond to ligands, not mechanical deformation (which is typical of mechanosensitive channels).
When educating patients who are starting on inhaled corticosteroids, the provider should tell them that:
- A. They need to get any live vaccines before starting the medication
- B. Inhaled corticosteroids need to be used daily during asthma exacerbations to be effective
- C. Patients should rinse their mouths out after using the inhaled corticosteroid to prevent thrush
- D. They can triple the dose number of inhalations of medication during colds to prevent needing systemic steroids
Correct Answer: C
Rationale: Rinsing the mouth prevents oral thrush, a common side effect of inhaled corticosteroids; vaccines , exacerbation-only use , or dose tripling are incorrect.
Renal damage is a potential adverse effect of aminoglycosides. In what part of the kidney are aminoglycosides retained which causes this effect?
- A. Distal tubule
- B. Proximal tubule
- C. Loop of Henle
- D. Glomerulus
Correct Answer: B
Rationale: Aminoglycosides are nephrotoxic and accumulate in the proximal tubule, leading to cellular damage and potential renal impairment.
You prescribe bromocriptine for a woman with primary amenorrhea. Normal menstruation returns about a month after starting therapy. Which of the following statements best describes the mechanism by which bromocriptine caused its desired effects?
- A. Blocked estrogen receptors, enhanced gonadotropin release
- B. Increased FSH synthesis
- C. Inhibited prolactin release
- D. Stimulated ovarian estrogen and progestin synthesis
Correct Answer: C
Rationale: Bromocriptine, a dopamine agonist, inhibits prolactin, restoring ovulation in hyperprolactinemia.
Which of the following adverse effects may occur due to a dihydropyridine-type calcium channel blocker?
- A. Bradycardia
- B. Hepatic impairment
- C. Increased contractility
- D. Edema of the hands and feet
Correct Answer: D
Rationale: Dihydropyridines (e.g., amlodipine) cause peripheral edema due to vasodilation.