Which of the following statements best defines how a chemical becomes a drug?
- A. A chemical must have a proven therapeutic value or efficacy without severe toxicity or damaging properties to become a drug.
- B. A chemical becomes a drug when it is introduced into the body to cause a change.
- C. A chemical is considered a drug when the Food and Drug Administration (FDA) approves its release to be marketed.
- D. A chemical must have demonstrated therapeutic value to become a drug.
Correct Answer: A
Rationale: A chemical must undergo a series of tests to determine its therapeutic value and efficacy without severe toxicity or damaging properties before it is termed a drug. Test results are reported to the FDA, which may or may not give approval.
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A patient asks the nurse, What is a Drug Enforcement Agency (DEA) number? What is the nurse's best response?
- A. DEA Numbers are given to physicians and pharmacists when they register with the DEA to prescribe and dispense controlled substances.
- B. Physicians must have a DEA number in order to prescribe any type of medication for patients.
- C. DEA numbers are case numbers given when someone breaks the law involving a controlled substance.
- D. DEA numbers are contact numbers to talk with someone at the DEA when questions arise about controlled substances.
Correct Answer: A
Rationale: All pharmacists and physicians must register with the DEA. They are given numbers that are required before they can dispense or prescribe controlled substances. DEA numbers are only needed when prescribing controlled substances. A DEA number is neither a case number nor a phone number.
Valerian tea causes relaxation and can be used to help a patient fall asleep. Overdosage of valerian (more than 2.5 gm/dose) may lead to:
- A. Cardiac disturbances
- B. Central nervous system depression
- C. Respiratory depression
- D. Skin rashes
Correct Answer: A
Rationale: Valerian overdose can cause cardiac disturbances due to its sedative effects.
Mutations in receptor tyrosine kinases would most likely be associated with :
- A. Neurologic diseases
- B. Endocrine diseases
- C. Cancers
- D. Metabolic abnormalities
Correct Answer: C
Rationale: Receptor tyrosine kinases are often linked to uncontrolled cell growth when mutated, commonly associated with cancers.
Sallie has been taking 10 mg per day of prednisone for the past 6 months. She should be assessed for:
- A. Gout
- B. Iron deficiency anemia
- C. Osteoporosis
- D. Renal dysfunction
Correct Answer: C
Rationale: Chronic prednisone increases osteoporosis risk via bone loss; gout or anemia are less direct.
Beta 2 adrenergic receptor agonists:
- A. Relieve bronchospasms
- B. Potentiates hypertensive
- C. Catecholamine inhibits the reception
- D. Have porasympathominetic action on bronchi
Correct Answer: A
Rationale: Beta-2 adrenergic agonists, like salbutamol, relieve bronchospasms by relaxing bronchial smooth muscle, making them key in asthma and COPD management.