Nokea
Which of the following statements is correct?
- A. Most drags are absorbed in ionized form
- B. Basic drags are generally bound to plasma albumin
- C. Microsomal enzymes are located in the mitochondria of hepatic cells
- D. Blood brain barrier is deficient at the chemo receptor trigger-zone
Correct Answer: D
Rationale: The chemoreceptor trigger zone has a deficient blood-brain barrier, allowing drug access; others are incorrect.
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The clinic nurse is performing an admission assessment on a client. The nurse notes that the client is taking azelaic acid (Azelex). Because of the medication prescription, the nurse would suspect that the client is being treated for:
- A. Acne
- B. Eczema
- C. Hair loss
- D. Herpes simplex
Correct Answer: A
Rationale: Azelaic acid is a topical medication used to treat mild to moderate acne. The acid appears to work by suppressing the growth of Propionibacterium acnes and decreasing the proliferation of keratinocytes. Options 2, 3, and 4 are incorrect.
Identify poor metabolizers of tamoxifen
- A. Not provided in document
- B. Not provided in document
- C. Not provided in document
- D. Not provided in document
Correct Answer: C
Rationale: This question lacks options, but the answer key (ANS: 3) indicates the third choice. Poor metabolizers of tamoxifen can be identified through CYP2D6 genotyping, as this enzyme converts tamoxifen to its active metabolite.
The average starting dose of warfarin is 5 mg daily. Higher doses of 7.5 mg daily should be considered in which patients?
- A. Pregnant women
- B. Elderly men
- C. Overweight or obese patients
- D. Patients with multiple comorbidities
Correct Answer: C
Rationale: Overweight/obese patients may need higher warfarin doses due to larger volume of distribution; pregnancy contraindicates warfarin.
Insuline:
- A. Facilitate glucose absorbtion in the small intestines
- B. Increase sensitivity of insuline receptors
- C. Facilitate glucose permeability in the cell and utilization
- D. Increase glycogen storage
Correct Answer: C
Rationale: Insulin facilitates glucose permeability and utilization and increases glycogen synthesis in cells.
When using a bar-code point-of-care medication system, the nurse would scan which of the following prior to drug administration?(Select one that does not apply.)
- A. Client's hospital chart
- B. Client's identification band
- C. Drug unit dose package
- D. Nurse's identification badge
Correct Answer: A
Rationale: The bar-code point-of-care medication system requires that the client's identification band, the drug unit dose package, and the nurse's identification badge are all scanned prior to drug administration.