Which of the following statements is not correct with regard to Mycobacterium tuberculosis and/or the disease it caused?
- A. The pathogen contains mycolic acid in the cell wall
- B. The pathogen can live intracellularly in macrophages
- C. The antibodies formed are protective
- D. None of the above
Correct Answer: C
Rationale: Rationale:
C is the correct answer because antibodies formed against Mycobacterium tuberculosis are not protective. They do not efficiently clear the infection due to the bacterium's ability to evade the immune response by residing intracellularly in macrophages. Antibodies play a minimal role in controlling tuberculosis compared to cell-mediated immunity.
Summary:
A is incorrect because Mycobacterium tuberculosis does contain mycolic acid in its cell wall. B is incorrect because the pathogen can indeed live intracellularly in macrophages. D is incorrect as C is the correct answer.
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Fungi are free-living _________ organisms:
- A. autotrophic
- B. chemotrophic
- C. heterotrophic
- D. phototrophic
Correct Answer: C
Rationale: The correct answer is C: heterotrophic. Fungi are heterotrophic organisms that obtain nutrients by absorbing organic compounds from their environment. They do not produce their own food through photosynthesis (option A: autotrophic) or chemosynthesis (option B: chemotrophic). Fungi also do not rely on light for energy (option D: phototrophic). Therefore, the correct choice is C as it accurately describes the nutritional mode of fungi.
N. Meningitidis grows on
- A. Levine agar
- B. Lowenstein-Jensen agar
- C. TCBS agar
- D. Chocolate agar
Correct Answer: D
Rationale: The correct answer is D: Chocolate agar. Neisseria meningitidis is a fastidious organism that requires enriched media for growth. Chocolate agar contains heat-treated blood that provides essential nutrients for the growth of N. meningitidis. The other choices, A: Levine agar, B: Lowenstein-Jensen agar, and C: TCBS agar, do not provide the specific nutrients required for the growth of N. meningitidis. Therefore, only choice D, Chocolate agar, supports the growth of N. meningitidis due to its enriched composition.
A patient presented with gas gangrene. Gram-positive rods producing spores and gas were isolated from a wound sample. Identify the microorganism.
- A. Clostridium perfringens
- B. Clostridium tetani
- C. Bacillus anthracis
- D. Staphylococcus aureus
Correct Answer: A
Rationale: The correct answer is A: Clostridium perfringens. Clostridium perfringens is known to cause gas gangrene and is a Gram-positive rod that produces spores and gas in tissue infections. Clostridium tetani causes tetanus, not gas gangrene. Bacillus anthracis causes anthrax, not gas gangrene. Staphylococcus aureus is a Gram-positive cocci and does not produce spores or gas in the context of gas gangrene. Therefore, based on the characteristics of the microorganism isolated from the wound sample, Clostridium perfringens is the most likely causative agent.
As an example of specific human parasites one can name Plasmodium falciparum, human pinworm and some others. The source of parasite invasion is always a human. Such specific human parasites cause the diseases that are called:
- A. Anthroponoses
- B. Zoonoses
- C. Anthropozoonoses
- D. Infections
Correct Answer: A
Rationale: The correct answer is A: Anthroponoses. This term refers to diseases caused by specific human parasites that are transmitted directly from human to human. In this case, the source of parasite invasion is always a human host. This term specifically describes diseases caused by parasites that exclusively infect humans.
Choice B: Zoonoses refers to diseases that can be transmitted from animals to humans. Choice C: Anthropozoonoses is a combination of zoonoses and anthroponoses, which is not applicable in this scenario. Choice D: Infections is a general term that does not specify the source or type of parasite causing the disease.
The Marburg virus was originally spread by:
- A. laboratory rats
- B. birds
- C. green monkeys
- D. wild turkeys
Correct Answer: C
Rationale: The correct answer is C: green monkeys. The Marburg virus was first identified in 1967 in Marburg and Frankfurt, Germany, after outbreaks in lab workers exposed to infected African green monkeys. These monkeys were imported from Uganda. The virus is believed to be originally endemic in certain species of African bats and is transmitted to humans through contact with infected animals. Choice A, laboratory rats, is incorrect as the virus did not originate from rats. Choice B, birds, and Choice D, wild turkeys, are also incorrect as there is no evidence linking these animals to the transmission of the Marburg virus.