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Which of the following statements is true regarding Joel's disorder? a.Hemophilia is an autosomal dominant disorder in which the woman carries the trait

  • A. Hemophilia follows regular laws of Mendelian inherited disorders such as sickle ceil anemia
  • B. This disorder can be carried by either male or female but occurs in the sex opposite that of the carrier
  • C. Hemophilia is an X-linked disorder in which the mother is usually the carrier of the illness but is not affected by it
Correct Answer: C

Rationale: Hemophilia is an X-linked disorder, meaning the gene responsible for hemophilia is carried on the X chromosome. Typically, hemophilia is passed down from a carrier mother to her male offspring who then express the disorder. This is because males have only one X chromosome (inherited from their mother), making them more vulnerable to X-linked disorders. Females have two X chromosomes, which means that even if one carries the hemophilia gene, the other X chromosome may carry a normal gene that can compensate, making females less likely to exhibit symptoms of hemophilia. In this case, Joel's disorder aligns with the typical pattern of inheritance for hemophilia as described in statement C.