Nokea
Which of the following statements regarding dietary approaches to obesity treatment is TRUE?
- A. Dietary modifications are generally not sustainable and hence dietary approaches are not as important as pharmacological approaches
- B. There is no Randomised Controlled Trial (RCT) level of evidence regarding decreasing sugar sweetened beverages
- C. Dietary approaches can be broadly categorised into energy-focused, macronutrient-focused, dietary pattern-focused, and dietary timing-focused
- D. Long-term diet trials have shown intermittent fasting to be superior to continuous energy restriction with respect to average weight loss
Correct Answer: C
Rationale: Diet's obesity fight splits smart energy, macros, patterns, and timing frame approaches, a true lens on options like low-carb or fasting. Sustainability varies, RCTs back sugar cuts, fasting ties (not tops) restriction, and proteins sate more than carbs. Clinicians wield this quartet, tailoring chronic plans, a broad truth in food's fat battle.
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A patient who is scheduled for a breast biopsy asks the nurse the difference between a benign tumor and a malignant tumor. Which answer by the nurse is correct?
- A. Benign tumors do not cause damage to other tissues.
- B. Benign tumors are likely to recur in the same location.
- C. Malignant tumors may spread to other tissues or organs.
- D. Malignant cells reproduce more rapidly than normal cells.
Correct Answer: C
Rationale: Malignant tumors metastasize spreading to distant sites via lymph or blood unlike benign ones, which stay put. That's the key split. Benign tumors can still mess up nearby tissues by pressing on them (e.g., a benign meningioma squeezing brain), so A's off. B's wrong benign tumors rarely recur if fully removed; malignancy's more prone to that. D's a myth malignant cells don't always divide faster; some, like chronic leukemia, creep along. Nurses in oncology nail this down for patients facing biopsies, like this breast case, where fear of spread drives the question. Explaining metastasis clarifies why malignant's scarier it's not just growth, it's invasion, a game-changer for prognosis and treatment.
In the treatment of COPD:
- A. Inhaled long-acting β₂ agonists are a first-line treatment for breathlessness.
- B. Most patients require maintenance use of oral corticosteroids.
- C. The dosage of oral theophylline needs to be reduced in patients commenced on erythromycin.
- D. Long-term oxygen therapy is indicated in a stable patient with a Paâ‚“â‚‚ of 8.5 kPa.
Correct Answer: C
Rationale: COPD management focuses on symptom relief and preventing exacerbations. Inhaled long-acting β₂ agonists are indeed used for breathlessness but are not always first-line; short-acting bronchodilators often precede them. Maintenance oral corticosteroids are not standard due to significant side effects; inhaled corticosteroids are preferred. Theophylline, a bronchodilator, has its metabolism inhibited by erythromycin (a CYP3A4 inhibitor), increasing plasma levels and toxicity risk, necessitating dose reduction. Long-term oxygen therapy is indicated for severe hypoxemia (Paₓ₂ < 7.3 kPa or 7.3-8 kPa with complications), not at 8.5 kPa, which is relatively normal. Non-invasive ventilation is reserved for acute exacerbations, not first-line treatment. The interaction between theophylline and erythromycin is a critical pharmacological consideration in COPD management, making it the standout correct statement.
Post exposure prophylaxis against Human Immunodeficiency Virus (HIV):
- A. is probably not effective when commenced 36 hours post exposure
- B. is administered intramuscularly
- C. is generally well-tolerated by patients
- D. when given, precludes the need for follow up serology
Correct Answer: C
Rationale: HIV PEP tolerable pills, not IM, works past 36 hours, needs serology, safe in pregnancy. Nurses dose this chronic shield easy.
Proven treatment for patients with noncirrhosis from NAFLD include the following except:
- A. Liver transplant
- B. Bariatric surgery
- C. Vitamin E
- D. Weight loss
Correct Answer: A
Rationale: Noncirrhotic NAFLD bends to weight loss, bariatric cuts, and Vitamin E's antioxidant punch proven aids. Transplant's endgame for cirrhosis, not here. Metformin flops for fat, despite diabetes use. Clinicians skip this organ swap, leaning on lifestyle and pills, a chronic fix before scars hit.
Epigenetic changes play a role in the development of type 2 diabetes mellitus. Question: Which of the following statements about epigenetics is correct?
- A. Epigenetic modifications lead to mutations in DNA
- B. Mutations in DNA lead to epigenetic modifications
- C. Epigenetic modifications only take place at a young age
- D. None of the statements provided above is correct
Correct Answer: D
Rationale: Epigenetics tweaks gene dials no mutations, not from mutations, not age-locked. Diet, stress flip switches anytime, a chronic type 2 player nurses note this, no false leads fit.