Which of the following statements regarding Single Nucleotide Polymorphisms (SNPs) in humans is NOT TRUE?
- A. SNPs occur at a frequency of about once every 300 nucleotides
- B. they are a rare source of genetic polymorphisms
- C. a polymorphism leading to increased IL-6 expression is associated with greater mortality
- D. none of the above are true
Correct Answer: B
Rationale: The correct answer is B because SNPs are actually a common source of genetic polymorphisms, occurring frequently in the human genome. SNPs are variations in a single nucleotide base and are estimated to occur once every 300 nucleotides. Choice A is incorrect because of this high frequency. Choice C is also incorrect as certain SNPs can indeed impact gene expression and health outcomes. Choice D is incorrect because B is not true, making the statement false. In summary, B is the correct answer as SNPs are not rare but rather common genetic variations in humans.
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What condition should the nurse anticipate when caring for a patient with a history of a total gastrectomy?
- A. Constipation
- B. Dehydration
- C. Elevated total serum cholesterol
- D. Cobalamin (vitamin B ) deficiency
Correct Answer: D
Rationale: The correct answer is D: Cobalamin (vitamin B12) deficiency. After a total gastrectomy, the patient lacks the intrinsic factor needed for vitamin B12 absorption in the ileum, leading to deficiency. This can result in megaloblastic anemia, neurological symptoms, and fatigue.
A: Constipation is not typically associated with total gastrectomy.
B: Dehydration may occur postoperatively but is not a specific consequence of total gastrectomy.
C: Elevated total serum cholesterol is not a direct effect of total gastrectomy.
Which of the following statements correctly describes GABA (gamma-amino butyric acid)?
- A. GABA is released at the presynaptic terminal to inhibit dopamine release
- B. GABA is released by GABA neurons and blocks propagation of the dopamine-triggered signal in the post synapse
- C. heroin and morphine stimulate GABA release
- D. all of the above are true
Correct Answer: B
Rationale: Rationale: Choice B is correct because GABA is indeed released by GABA neurons and acts to inhibit the propagation of signals triggered by dopamine in the post-synaptic neuron. GABA functions as an inhibitory neurotransmitter in the central nervous system. Choices A and C are incorrect. Choice A is inaccurate because GABA inhibits the release of dopamine, not the other way around. Choice C is incorrect as heroin and morphine act on opioid receptors, not GABA receptors. Choice D is incorrect because not all statements are true.
A male client with a recent history of rectal bleeding is being prepared for a colonoscopy. How should the nurse position the client for this test initially?
- A. Lying on the right side with legs straight
- B. Lying on the left side with knees bent
- C. Prone with the torso elevated
- D. Bent over with hands touching the floor
Correct Answer: B
Rationale: The correct answer is B: Lying on the left side with knees bent. This position allows for better visualization and access to the colon during the colonoscopy procedure. By lying on the left side, the client's colon is in a more optimal position for the scope to navigate through the colon. Additionally, bending the knees helps to relax the abdominal muscles and make the procedure more comfortable for the client.
Incorrect choices:
A: Lying on the right side with legs straight - This position does not provide optimal access to the colon and may make the procedure more difficult.
C: Prone with the torso elevated - This position is not suitable for a colonoscopy as it does not allow for proper access to the colon.
D: Bent over with hands touching the floor - This position is not recommended for a colonoscopy as it is not conducive to the procedure and may cause discomfort for the client.
A nurse is instructing a client who has GERD about positions that can help minimize the effects of reflux during sleep. Which of the following statements indicates to the nurse that the client understands the instructions?
- A. I will lie on my left side to sleep at night.'
- B. I will lie on my right side to sleep at night.'
- C. I will sleep on my back with my head flat.'
- D. I will sleep on my stomach with my head flat.'
Correct Answer: A
Rationale: The correct answer is A: "I will lie on my left side to sleep at night." This position helps prevent acid from flowing back into the esophagus due to the angle of the stomach in relation to the esophagus. Lying on the right side can worsen reflux. Sleeping on the back with the head flat can also worsen symptoms as gravity can allow acid to flow back up. Sleeping on the stomach with the head flat is not recommended as it can put pressure on the stomach, leading to increased reflux.
The patient has peritonitis, which is a major complication of appendicitis. What treatment will the nurse plan to include?
- A. Peritoneal lavage
- B. Peritoneal dialysis
- C. IV fluid replacement
- D. Increased oral fluid intake
Correct Answer: C
Rationale: The correct answer is C: IV fluid replacement. IV fluids are essential in managing peritonitis to maintain hydration and electrolyte balance. It helps to support the patient's circulation and prevent shock. Peritoneal lavage (choice A) is not typically used in the treatment of peritonitis. Peritoneal dialysis (choice B) is used for kidney failure, not peritonitis. Increased oral fluid intake (choice D) may not be sufficient in cases of peritonitis where IV fluids are needed for rapid rehydration and support.