Nokea
Which statement best describes drug efficacy/toxicity in pediatric clients?
- A. Drug requirements for infants have been extensively studied.
- B. Drug dosage is altered by age and weight in children.
- C. Children always need smaller doses of medication than adults.
- D. Infants and children are always at greater risk for drug toxicity with any medication.
Correct Answer: B
Rationale: Pediatric dosing adjusts for age and weight to ensure efficacy and minimize toxicity, reflecting developmental differences.
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Which of the following is the frequent cause of nausea and vomiting:
- A. While using insulin medications
- B. While treated with acarbose
- C. While treated with metformin
- D. While treated with glibenclamid
Correct Answer: C
Rationale: Metformin commonly causes nausea and vomiting due to gastrointestinal irritation.
Nicotine has a variety of effects on nicotinic receptors throughout the body. Which of the following is NOT an effect of nicotine?
- A. Vasodilation and decreased heart rate
- B. Increased secretion of gastric acid and motility of the GI smooth muscle
- C. Release of dopamine at the pleasure center
- D. Stimulation of the locus coeruleus
Correct Answer: A
Rationale: Nicotine causes vasoconstriction and increased heart rate, not vasodilation.
Vitamin B2 (riboflavin) may be prescribed to:
- A. Decrease the incidence of beriberi
- B. Reduce headaches and migraines
- C. Prevent pernicious anemia
- D. Treat hyperlipidemia
Correct Answer: B
Rationale: Riboflavin has been used to reduce migraine frequency, though evidence is limited.
Besides cystic fibrosis, which other medical state may trigger the need for pancreatic enzymes?
- A. Paget's disease
- B. Pulmonary cancers
- C. Gallbladder surgery
- D. Some bariatric surgeries
Correct Answer: D
Rationale: Bariatric surgeries like gastric bypass can impair pancreatic function, necessitating enzymes; gallbladder doesn't typically.
A 66-year-old male was prescribed phenelzine (Nardil) while in an acute psychiatric unit for recalcitrant depression. The NP managing his primary health care needs to understand the following regarding phenelzine and other monoamine oxidase inhibitors (MAOIs):
- A. He should not be prescribed any serotonergic drug such as sumatriptan (Imitrex)
- B. MAOIs interact with many common foods, including yogurt, sour cream, and soy sauce
- C. Symptoms of hypertensive crisis (headache, tachycardia, sweating) require immediate treatment
- D. All of the above
Correct Answer: D
Rationale: MAOIs have serotonergic interactions, food restrictions (tyramine), and hypertensive crisis risks.