Genitourinary System Quizlet Related

Review Genitourinary System Quizlet related questions and content

Which statement best describes Zidovudine: *

  • A. Zidovudine in combination with other antiretrovirals is an alternative initial treatment for HIV infection.
  • B. Zidovudine is also used to prevent transmission of HIV from the mother to her
  • C. Zidovudine is converted by cellular enzymes to an active form, zidovudine diphosphate, which prevents viral DNA from replicating.
  • D. Peripheral neuropathy is a specic adverse reaction to Zidovudine
Correct Answer: C

Rationale: Rationale for Correct Answer (C):
1. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI) used in the treatment of HIV.
2. Zidovudine is indeed converted by cellular enzymes to its active form, zidovudine diphosphate.
3. Zidovudine diphosphate inhibits the reverse transcriptase enzyme, preventing viral DNA replication in HIV-infected cells.
4. This mechanism of action is crucial in reducing viral load and slowing disease progression in HIV patients.

Summary of Incorrect Choices:
A: Incorrect. While Zidovudine is used in combination therapy for HIV, it is not typically an alternative initial treatment.
B: Incorrect. Zidovudine can be used to prevent mother-to-child transmission of HIV, but it is not its primary indication.
D: Incorrect. Peripheral neuropathy is not a specific adverse reaction to Zidovudine; rather, it is more commonly associated with