Nokea
Which statement is false of Domperidone
- A. Chemically related to haloperidol
- B. Pharmacologically related to metoclopramide
- C. Extra pyramidal symptoms are common
- D. It counteracts the emetic action but not the therapeutic effect in parkinsonism
Correct Answer: C
Rationale: Domperidone rarely causes extrapyramidal symptoms as it doesn't cross the blood-brain barrier.
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Vitamin B2 (riboflavin) may be prescribed to:
- A. Decrease the incidence of beriberi
- B. Reduce headaches and migraines
- C. Prevent pernicious anemia
- D. Treat hyperlipidemia
Correct Answer: B
Rationale: Riboflavin has been used to reduce migraine frequency, though evidence is limited.
Which of the following is the frequent cause of nausea and vomiting:
- A. While using insulin medications
- B. While treated with acarbose
- C. While treated with metformin
- D. While treated with glibenclamid
Correct Answer: C
Rationale: Metformin commonly causes nausea and vomiting due to gastrointestinal irritation.
Digoxin may cause a type A adverse drug reaction due to:
- A. Idiosyncratic effects
- B. Its narrow therapeutic index
- C. Being a teratogen
- D. Being a carcinogen
Correct Answer: B
Rationale: Digoxin's narrow therapeutic index leads to Type A (dose-related) ADRs like toxicity, not idiosyncratic or teratogenic/carcinogenic effects .
Which of the following reflects a nurse's responsibility when a drug is prescribed for a client? (Select one that does not apply.)
- A. Administering the drug to the client
- B. Monitoring for therapeutic response
- C. Checking for drug-drug interactions
- D. Reporting adverse reactions
Correct Answer: C
Rationale: When a drug is prescribed to a client, the nurse is responsible for the administration of the drug, monitoring for therapeutic effects, reporting adverse drug reactions, and teaching the client information needed to administer the drug safely at home. A pharmacist checks for drug-drug interactions prior to dispensing a drug for administration.
Which of the following adverse effects may occur due to a dihydropyridine-type calcium channel blocker?
- A. Bradycardia
- B. Hepatic impairment
- C. Increased contractility
- D. Edema of the hands and feet
Correct Answer: D
Rationale: Dihydropyridines (e.g., amlodipine) cause peripheral edema due to vasodilation.