Nokea
Which of the following is antithyroidal drugs:
- A. Thyroxine
- B. Liothironine
- C. Propilthyouracil
- D. Triiodthironine
Correct Answer: C
Rationale: Propilthyouracil (propylthiouracil) is an antithyroid drug that inhibits thyroid hormone synthesis by blocking the iodination of tyrosine residues in thyroglobulin.
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Patients with rheumatoid arthritis who are on chronic low-dose prednisone will need co-treatment with which medications to prevent further adverse effects?
- A. A bisphosphonate
- B. Calcium supplementation
- C. Vitamin D
- D. All of the above
Correct Answer: D
Rationale: All mitigate prednisone's bone loss: bisphosphonates , calcium , and vitamin D .
The first laboratory value indication that vitamin B12 therapy is adequately treating pernicious anemia is:
- A. Hematocrit levels start to rise
- B. Hemoglobin levels return to normal
- C. Reticulocyte count begins to rise
- D. Vitamin B12 levels return to normal
Correct Answer: C
Rationale: Reticulocyte count rise signals early bone marrow response to B12, preceding hemoglobin or hematocrit increases.
Prescribing less-expensive generic drugs or drugs off the 4 retail pharmacy lists:
- A. Increases the complexity of the pharmacoeconomics of prescribing for the individual patient
- B. Increases compliance by reducing the financial burden of drug costs to the patient
- C. Is not sound prescribing practice due to the inferiority of the generic products
- D. Will increase the overall cost of drugs to the system due to the ease of overprescribing less-expensive drugs
Correct Answer: B
Rationale: Generic drugs improve adherence by lowering patient costs.
Where are tight junctions created by two adjoining cells located?
- A. Bone
- B. Brain
- C. Skin
- D. Liver
Correct Answer: B
Rationale: Tight junctions are prominent in the brain (blood-brain barrier), restricting drug entry, unlike the liver (fenestrated) or bone/skin (different barriers).
A nurse is teaching a client who has a new prescription for digoxin to treat heart failure. Which of the following instructions should the nurse include in the teaching?
- A. Contact provider if heart rate is less than 60/min.
- B. Check pulse rate for 30 seconds and multiply result by 2.
- C. Increase intake of sodium.
- D. Take with food if nausea occur
Correct Answer: A
Rationale: Bradycardia (<60/min, A) is a sign of digoxin toxicity to report; pulse should be checked for 1 minute.