Nokea
Which statement is not correct regarding acarbose:
- A. Is for internal use
- B. Inhibiting alfa glucosidase
- C. Inhibits carbohydrates absorbtion in the gut
- D. Is effective for diabetes mellitus type I
Correct Answer: D
Rationale: Acarbose is primarily effective for type 2 diabetes by delaying carbohydrate absorption, not type 1, which relies on insulin deficiency.
You may also like to solve these questions
Which of the following combinations of drugs should be used in the treatment of a patient with organophosphate poisoning?
- A. Atropine and epinephrine
- B. Epinephrine and isoproterenol
- C. Norepinephrine and propranolol
- D. Atropine and pralidoxime
Correct Answer: D
Rationale: Atropine blocks muscarinic effects, and pralidoxime regenerates cholinesterase.
You are to infuse 1,200 mL of IV fluid over 6 hours using a drop factor of 10 gtt/mL. What is the flow rate in drops per minute?
- A. 30 gtt/min
- B. 33 gtt/min
- C. 40 gtt/min
- D. 50 gtt/min
Correct Answer: B
Rationale: Flow rate = (1,200 mL 10 gtt/mL) ÷ (6 60) = 12,000 ÷ 360 = 33.33 gtt/min, rounded to 33 gtt/min.
A drug which does not produce any action by itself but decreases the slope of the log dose-response curve and suppresses the maximal response to another drug is a...
- A. Physiological antagonist
- B. Competitive antagonist
- C. Noncompetitive antagonist
- D. Partial agonist
Correct Answer: C
Rationale: Noncompetitive antagonists reduce maximal response (efficacy) without shifting potency, matching the description.
Up to 21% of Asians are ultra-rapid 2D6 metabolizers, requiring:
- A. A need to monitor drugs metabolized by 2D6 for toxicity
- B. Increased dosages needed of drugs metabolized by 2D6, such as the selective serotonin reuptake inhibitors
- C. Decreased conversion of codeine to morphine by CYP 2D6
- D. The need for lowered dosages of drugs, such as beta blockers
Correct Answer: B
Rationale: Ultra-rapid 2D6 metabolizers (e.g., in Asians) need higher SSRI doses due to fast metabolism, unlike toxicity , codeine issues , or lower doses .
A 73-year-old male patient is being discharged home today. The discharge order reads: Take 10 mL of guaifenesin (Robitussin) PO q4h. This over-the-counter pharmaceutical comes in bottles with plastic measuring caps. How much should the nurse teach the patient to take at home?
- A. 1/2 tsp
- B. 1 tsp
- C. 2 tsp
- D. 1 tbsp
Correct Answer: C
Rationale: 10 mL equals 2 teaspoons (5 mL = 1 tsp), so the patient should take 2 tsp per dose.