Nokea
Why are endothelial cells in particular sensitive to the damage caused by high plasma glucose levels?
- A. Endothelial cells have a high metabolic activity
- B. Endothelial cells cannot regulate the glucose uptake
- C. Endothelial cells have a low level of antioxidants
- D. All statements provided above are correct
Correct Answer: B
Rationale: Endothelial cells drown in glucose no uptake brakes, high sugar slams them, not just metabolism or low shields. A chronic vessel weak spot nurses watch this sugar soak.
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Chemotherapeutic treatment of acute leukemia is done in four phases. Place these phases in the correct order.
- A. Maintenance
- B. Induction
- C. Intensification
- D. Consolidation
Correct Answer: B
Rationale: Acute leukemia's chemotherapy unfolds systematically: induction kicks off, aggressively killing leukemia cells to induce remission, a high-dose blitz. Intensification follows, targeting residual cells over months, relentless in early remission. Consolidation reinforces, eliminating lingering blasts post-remission, solidifying gains. Maintenance, with lower doses, sustains remission long-term, preventing relapse. This order induction, intensification, consolidation, maintenance mirrors the disease's need for initial eradication then sustained control, a structured approach nurses reinforce through patient education and monitoring, ensuring each phase's purpose aligns with leukemia's aggressive biology and treatment goals.
What is the cut-off of blood pressure for the diagnosis of hypertension that is recommended by MOH Clinical Practice Guideline?
- A. 120/70 mmHg
- B. 125/75 mmHg
- C. 130/70 mmHg
- D. 140/90 mmHg
Correct Answer: D
Rationale: MOH guidelines hold hypertension at 140/90 mmHg, a conventional cutoff balancing sensitivity and specificity for diagnosis in primary care, aligning with global norms like WHO. Lower thresholds 120/70, 125/75, 130/70, 135/80 catch prehypertension or align with newer AHA standards, but MOH sticks to 140/90 for actionable clarity, triggering treatment to curb stroke or heart risks. This higher bar avoids overdiagnosis in resource-stretched settings, ensuring focus on clear disease, a practical call for managing chronic vascular load.
The nurse is reviewing laboratory values for a client. Which of the following lab values should the nurse address immediately?
- A. Potassium 5.9 mmol/L
- B. Phosphorus 5.1 mg/dL
- C. Creatinine 6.2 mg/dL
- D. Sodium 147 mEq/L
Correct Answer: A
Rationale: Potassium 5.9 mmol/L above 5.5 sparks hyperkalemia, risking arrhythmias, a now-or-never fix over phosphorus's mild bump (3.0-4.5 normal). Creatinine's renal cry waits; sodium's high but tolerable. Nurses jump on potassium, anticipating ECG or kayexalate, a heart-stopping lab in this urgent sweep.
A primary nursing responsibility is the prevention of lung cancer by assisting patients in smoking/tobacco cessation. Which tasks would be appropriate to delegate to the LPN/LVN?
- A. Develop a quit plan
- B. Explain the application of a nicotine patch
- C. Discuss strategies to avoid relapse
- D. Suggest ways to deal with urges for a tobacco
Correct Answer: B
Rationale: LPN/LVNs shine in standardized teaching like explaining nicotine patch application, a medication-focused task within their scope, detailing placement and timing to aid cessation. Developing a quit plan requires RN-level planning and assessment of individual needs. Discussing relapse strategies involves behavioral counseling, an RN forte. Suggesting urge-coping methods needs tailored insight, beyond LPN/LVN training. Patch explanation leverages their skills, supporting lung cancer prevention through practical cessation aid, a delegated task enhancing team efforts while keeping complex planning with RNs.
Dexmedetomidine:
- A. Is recognized as an α₠receptor agonist.
- B. Increases the minimum alveolar concentration of volatile agents.
- C. Causes bradycardia.
- D. Has a loading dose of 0.5-1.0 μg kgâ»Â¹.
Correct Answer: C
Rationale: Dexmedetomidine is a highly selective α₂-adrenergic receptor agonist, not αâ‚, used for sedation with minimal respiratory depression. It reduces the minimum alveolar concentration of volatile anesthetics by enhancing sedation and analgesia, not increasing it. Bradycardia is a well-known side effect due to its sympatholytic action, decreasing heart rate via vagal stimulation and reduced catecholamine release. The standard loading dose is indeed 0.5-1.0 μg kgâ»Â¹ over 10 minutes, followed by infusion, aligning with clinical protocols. At high infusion rates, respiratory depression is unlikely, distinguishing it from opioids. Bradycardia's prominence as a side effect stems from its mechanism activation of α₂ receptors in the brainstem and periphery inhibits sympathetic outflow, making it a critical consideration in perioperative management, especially in patients with cardiovascular comorbidities.