Health Promotion and Disease Prevention Questions Related

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You are investigating the role of physical activity in heart disease, and your data suggest a protective effect. While presenting your findings, a colleague asks whether you have thought about confounders, such as factor X. Under which of the following conditions could this factor have confounded your interpretation of the data?

  • A. It is a risk factor for some other disease, but not heart disease.
  • B. It is a risk factor associated with the physical activity measure and heart disease.
  • C. It is part of the causal pathway by which physical activity affects heart disease.
  • D. It has caused a lack of follow-up of test subjects.
Correct Answer: B

Rationale: A confounder must be associated with both the exposure (physical activity) and the outcome (heart disease), and it should not lie on the causal pathway between them.